Tumor Necrosis Factor Alpha Influences the Inflammatory Response After Coronary Surgery

A systemic inflammatory response is not uncommonly observed after coronary revascularization. Tumor necrosis factor alpha is one of a number of modulators of this response. A functional polymorphism within the TNFα gene at position G-308A has been associated with increased TNFα levels. The relations...

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Veröffentlicht in:	The Annals of thoracic surgery 2006, Vol.81 (1), p.132-137
Hauptverfasser:	Bittar, Mohamad N., Carey, John A., Barnard, James B., Pravica, Vera, Deiraniya, Abdul K., Yonan, Nizar, Hutchinson, Ian V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cardiopulmonary Bypass - adverse effects DNA Mutational Analysis Elective Surgical Procedures Female Genetic Predisposition to Disease Genotype Humans Male Middle Aged Myocardial Revascularization Polymerase Chain Reaction Polymorphism, Single Nucleotide Postoperative Complications - etiology Postoperative Complications - physiopathology Risk Factors Systemic Inflammatory Response Syndrome - etiology Systemic Inflammatory Response Syndrome - genetics Systemic Inflammatory Response Syndrome - physiopathology Treatment Outcome Tumor Necrosis Factor-alpha - analysis Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - physiology
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