Effect of atorvastatin on circulating proinflammatory T-lymphocyte subsets and soluble CD40 ligand in patients with stable coronary artery disease—A randomized, placebo-controlled study

Coronary atherosclerosis includes an activation of circulating T lymphocytes. Statins exert anti-inflammatory effects beyond lipid lowering. Whether these properties influence systemic T lymphocytes is unclear. To investigate the effect of atorvastatin on circulating T-lymphocyte subsets producing p...

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Veröffentlicht in:	The American heart journal 2006, Vol.151 (1), p.139.e1-139.e7
Hauptverfasser:	Alber, Hannes Franz, Frick, Matthias, Suessenbacher, Alois, Doerler, Jakob, Schirmer, Michael, Stocker, Eva-Maria, Dichtl, Wolfgang, Pachinger, Otmar, Weidinger, Franz
Format:	Artikel
Sprache:	eng
Schlagworte:	Atorvastatin Calcium CD40 Ligand - blood Cholesterol Coronary Artery Disease - blood Coronary Artery Disease - drug therapy Cytokines - blood Drug therapy Female Heart attacks Heptanoic Acids - pharmacology Heptanoic Acids - therapeutic use Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Low density lipoprotein Lymphocytes Male Middle Aged Pyrroles - pharmacology Pyrroles - therapeutic use T-Lymphocyte Subsets - drug effects T-Lymphocyte Subsets - immunology
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