CD14 and CD169 expression in human lymph nodes and spleen: specific expansion of CD14 +CD169 − monocyte-derived cells in diffuse large B-cell lymphomas

The mononuclear phagocyte system of human lymphoid tissue comprises macrophages and dendritic cells (DCs). The heterogeneity of the non-DC mononuclear phagocyte population in human lymphoid tissue has been little addressed. Here, we studied the expression of 2 monocyte-derived markers, CD14 and CD16...

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Veröffentlicht in:	Human pathology 2006, Vol.37 (1), p.68-77
Hauptverfasser:	Marmey, Béatrice, Boix, Charlotte, Barbaroux, Jean-Baptiste, Dieu-Nosjean, Marie-Caroline, Diebold, Jacques, Audouin, Josée, Fridman, Wolf-Herman, Mueller, Chris G.F., Molina, Thierry J.
Format:	Artikel
Sprache:	eng
Schlagworte:	B-cell lymphomas Biological and medical sciences Biomarkers, Tumor - metabolism CD14 Cell Separation Dendritic Cells - metabolism Dendritic Cells - pathology Expansion Flow Cytometry Fluorescent Antibody Technique, Direct Hematologic and hematopoietic diseases Humans Immunoenzyme Techniques Investigative techniques, diagnostic techniques (general aspects) Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lipopolysaccharide Receptors - metabolism Lymph Nodes - metabolism Lymph Nodes - pathology Lymphadenitis - metabolism Lymphadenitis - pathology Lymphoma Lymphoma, B-Cell - metabolism Lymphoma, B-Cell - pathology Lymphoma, Large B-Cell, Diffuse - metabolism Lymphoma, Large B-Cell, Diffuse - pathology Medical sciences Membrane Glycoproteins - metabolism Monocytes - metabolism Monocytes - pathology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Proteins Receptors, Immunologic - metabolism Sialic Acid Binding Ig-like Lectin 1 Sialoadhesin Spleen Spleen - metabolism Spleen - pathology Tumor microenvironment
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