Cdx4 is a direct target of the canonical Wnt pathway

There is considerable evidence that the Cdx gene products impact on vertebral patterning by direct regulation of Hox gene expression. Data from a number of vertebrate model systems also suggest that Cdx1, Cdx2 and Cdx4 are targets of caudalizing signals such as RA, Wnt and FGF. These observations ha...

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Veröffentlicht in:	Developmental biology 2006, Vol.289 (1), p.55-63
Hauptverfasser:	Pilon, Nicolas, Oh, Karen, Sylvestre, Jean-René, Bouchard, Nathalie, Savory, Joanne, Lohnes, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta Catenin - analysis beta Catenin - metabolism Body Patterning - genetics Cdx Chromatin Immunoprecipitation Embryo, Mammalian - chemistry Embryo, Mammalian - metabolism Female Gene Expression Regulation, Developmental Homeodomain Proteins - genetics LEF/TCF Lymphoid Enhancer-Binding Factor 1 - analysis Lymphoid Enhancer-Binding Factor 1 - metabolism Mice Mice, Mutant Strains Promoter Regions, Genetic - drug effects Response Elements Signal Transduction Transcription Tumor Cells, Cultured Vertebral patterning Wnt Wnt Proteins - genetics Wnt Proteins - metabolism Wnt Proteins - pharmacology Wnt3 Protein Wnt3A Protein
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