Signalling pathway in the induction of neurite outgrowth in human mesenchymal stem cells

Recent in vivo transplantation studies have shown that mesenchymal stem cells (MSCs) were able to differentiate into mesoderm-derived cell types as well as cells with neuroectodermal characteristics, suggesting that transdifferentiation occurs in the mammalian system. We have reported an immortalize...

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Veröffentlicht in:	Cellular signalling 2006-04, Vol.18 (4), p.519-530
Hauptverfasser:	Chu, Mien-Sheng, Chang, Ching-Fang, Yang, Chuan-Ching, Bau, Yi-Chi, Ho, Larry Low-Tone, Hung, Shih-Chieh
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Methyl-3-isobutylxanthine - pharmacology cAMP–PKA Colforsin - pharmacology Cyclic AMP Response Element-Binding Protein - metabolism Cyclic AMP-Dependent Protein Kinases - drug effects Cyclic AMP-Dependent Protein Kinases - metabolism Female Human mesenchymal stem cells Humans Immortalization MAPK–ERK Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - metabolism Middle Aged Mitogen-Activated Protein Kinase 1 - metabolism Mitogen-Activated Protein Kinase 3 - metabolism Neurite outgrowth Neurites - drug effects Neurites - metabolism Neuroepithelial cells Phosphorylation Signal Transduction - drug effects Signal Transduction - physiology Time Factors
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