Intestinal and oncocytic variants of pancreatic intraepithelial neoplasia. A morphological and immunohistochemical study

We report 2 previously undescribed morphological variants of pancreatic intraepithelial neoplasia (PanIN). The first variant with an intestinal phenotype was associated with mucinous carcinomas that occurred in the tail of the pancreas of 2 men (60 and 65 years old). The carcinomas lacked the charac...

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Veröffentlicht in:	Annals of diagnostic pathology 2005-04, Vol.9 (2), p.69-76
Hauptverfasser:	Albores-Saavedra, Jorge, Wu, Jianhua, Crook, Terri, Amirkhan, Robin H., Jones, Lamar, Hruban, Ralph H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Mucinous - genetics Adenocarcinoma, Mucinous - metabolism Adenocarcinoma, Mucinous - pathology Aged Carcinoma in Situ - genetics Carcinoma in Situ - metabolism Carcinoma in Situ - pathology Humans Immunohistochemistry Intestinal and oncocytic variants Intestines - pathology Male Middle Aged MUC-1 MUC-2 Mucin-1 - metabolism Mucin-2 Mucins - metabolism Oxyphil Cells - pathology Pancreatic intraepithelial neoplasia Pancreatic Neoplasms - genetics Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology Phenotype
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