Interleukin-10 promoter polymorphism is associated with decreased breast cancer risk

Interleukin-10 (IL-10) is an immunosuppressive cytokine which may facilitate development of cancer by supporting tumor escape from the immune response. A [TCATA] haplotype formed by polymorphisms at positions -3575, -2763, -1082, -819 and -592 in the promoter of the IL-10 gene is a strong determinan...

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Veröffentlicht in:	Breast cancer research and treatment 2005-03, Vol.90 (2), p.113-115
Hauptverfasser:	LANGSENLEHNER, Uwe, KRIPPL, Peter, RENNER, Wilfried, YAZDANI-BIUKI, Babak, EDER, Tanja, KÖPPEL, Herwig, WASCHER, Thomas C, PAULWEBER, Bernhard, SAMONIGG, Hellmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Austria - epidemiology Biological and medical sciences Breast cancer Breast Neoplasms - epidemiology Breast Neoplasms - genetics Cancer research Case-Control Studies Cytokines Epidemiology Female Genetic Predisposition to Disease - epidemiology Genetic Predisposition to Disease - genetics Genetics Gynecology. Andrology. Obstetrics Haplotypes - genetics Humans Interleukin-10 - genetics Mammary gland diseases Matched-Pair Analysis Medical research Medical sciences Polymorphism Polymorphism, Genetic Promoter Regions, Genetic - genetics Risk Tumors
Online-Zugang:	Volltext
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