Leisure Time Physical Activity Is Associated With Poor Glycemic Control in Type 1 Diabetic Women: The FinnDiane study
OBJECTIVE:--We studied the association between leisure time physical activity (LTPA) and glycemic control, insulin dose, and estimated glucose disposal rate (eGDR) in type 1 diabetes. RESEARCH DESIGN AND METHODS--This is a cross-sectional study of 1,030 type 1 diabetic patients participating in the...
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| Veröffentlicht in: | Diabetes care 2005-04, Vol.28 (4), p.777-782 |
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| creator | Wadén, Johan Tikkanen, Heikki Forsblom, Carol Fagerudd, Johan Pettersson-Fernholm, Kim Lakka, Timo Riska, Mikael Groop, Per-Henrik |
| description | OBJECTIVE:--We studied the association between leisure time physical activity (LTPA) and glycemic control, insulin dose, and estimated glucose disposal rate (eGDR) in type 1 diabetes. RESEARCH DESIGN AND METHODS--This is a cross-sectional study of 1,030 type 1 diabetic patients participating in the Finnish Diabetic Nephropathy Study, a nationwide multicenter study. LTPA was assessed by a validated 12-month questionnaire and expressed in metabolic equivalent (MET) units. Patients were grouped as sedentary (LTPA 40 MET h/week, n = 215). Outcome measures were HbA[subscript 1c], insulin dose, and eGDR (estimate of insulin sensitivity based on waist-to-hip ratio, hypertension, and HbA[subscript 1c]). RESULTS:--LTPA correlated with HbA[subscript 1c] in women (r = -0.12, P = 0.007) but not in men (r = -0.03, P = 0.592). Sedentary women had higher HbA[subscript 1c] than moderately active and active women: 8.8 ± 1.4% vs. 8.3 ± 1.4% vs. 8.3 ± 1.4% (P = 0.004), whereas HbA[subscript 1c] in men was 8.4 ± 1.3% vs. 8.2 ± 1.4% vs. 8.2 ± 1.3% (P = 0.774), respectively. In men, insulin doses were 0.74 ± 0.21 vs. 0.71 ± 0.20 vs. 0.68 ± 0.23 IU · kg⁻¹ · 24 h⁻¹ (P = 0.003). In both sexes, sedentary patients had lower eGDRs than active patients [median (interquartile range) 5.5 (4.0-8.2) vs. 6.8 (4.7-8.8) vs. 6.7 (4.6-8.6) mg · kg⁻¹ · min⁻¹; P < 0.01 for sedentary vs. others]. Age, obesity, smoking, insulin dose, social class, diabetic nephropathy, or cardiovascular disease did not explain the results. CONCLUSIONS:--Low levels of LTPA were associated with poor glycemic control in type 1 diabetic women. Men seem to use less insulin when physically active. Increased LTPA levels were associated with increased estimated insulin sensitivity. Longitudinal studies are needed to further clarify the effects of LTPA on type 1 diabetes. |
| doi_str_mv | 10.2337/diacare.28.4.777 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_67563566</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A131318453</galeid><sourcerecordid>A131318453</sourcerecordid><originalsourceid>FETCH-LOGICAL-f367t-39db60ac90bf59007e83737137c5f475643fc8e98cd41dfc6f0fe36e39e9040f3</originalsourceid><addsrcrecordid>eNpt0c-LEzEUB_BBFLeu3j1pEPQ2NZn89laquy4UXLDLHoc089JmmUlqMiPMf2-WVgRZ3iHw8smXR15VvSV42VAqP3feWJNg2aglW0opn1ULoimvOWfqebXAhOmaa91cVK9yfsAYM6bUy-qCcKkpkc2imjbg85QAbf0A6PYwZ29Nj1Z29L_9OKObjFY5R-vNCB269-MB3caY0HU_Wxi8ResYxhR75APazkdABH31ZgdjubqPA4QvaHsAdOVDKP0AKI9TN7-uXjjTZ3hzPi-ru6tv2_X3evPj-ma92tSOCjnWVHc7gY3VeOe4xliCopJKQqXljkkuGHVWgVa2Y6RzVjjsgAqgGjRm2NHL6tMp95jirwny2A4-W-j7MkmccitKBuVCFPjhP_gQpxTKbG3TUEyVJKSg-oT2pofWBxfHZOweAiTTxwDOl_aK0FKKcVr88glfqnv8uScfvDtPMe0G6Npj8oNJc_t3XQV8PAOTy5pcMsH6_M8JwRVmj0HvT86Z2Jp9KubuZ4MJxVgr3XBC_wAxC6wj</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>223038711</pqid></control><display><type>article</type><title>Leisure Time Physical Activity Is Associated With Poor Glycemic Control in Type 1 Diabetic Women: The FinnDiane study</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Wadén, Johan ; Tikkanen, Heikki ; Forsblom, Carol ; Fagerudd, Johan ; Pettersson-Fernholm, Kim ; Lakka, Timo ; Riska, Mikael ; Groop, Per-Henrik</creator><creatorcontrib>Wadén, Johan ; Tikkanen, Heikki ; Forsblom, Carol ; Fagerudd, Johan ; Pettersson-Fernholm, Kim ; Lakka, Timo ; Riska, Mikael ; Groop, Per-Henrik ; FinnDiane Study Group</creatorcontrib><description>OBJECTIVE:--We studied the association between leisure time physical activity (LTPA) and glycemic control, insulin dose, and estimated glucose disposal rate (eGDR) in type 1 diabetes. RESEARCH DESIGN AND METHODS--This is a cross-sectional study of 1,030 type 1 diabetic patients participating in the Finnish Diabetic Nephropathy Study, a nationwide multicenter study. LTPA was assessed by a validated 12-month questionnaire and expressed in metabolic equivalent (MET) units. Patients were grouped as sedentary (LTPA <10 MET h/week, n = 247), moderately active (LTPA 10-40 MET h/week, n = 568), and active (LTPA >40 MET h/week, n = 215). Outcome measures were HbA[subscript 1c], insulin dose, and eGDR (estimate of insulin sensitivity based on waist-to-hip ratio, hypertension, and HbA[subscript 1c]). RESULTS:--LTPA correlated with HbA[subscript 1c] in women (r = -0.12, P = 0.007) but not in men (r = -0.03, P = 0.592). Sedentary women had higher HbA[subscript 1c] than moderately active and active women: 8.8 ± 1.4% vs. 8.3 ± 1.4% vs. 8.3 ± 1.4% (P = 0.004), whereas HbA[subscript 1c] in men was 8.4 ± 1.3% vs. 8.2 ± 1.4% vs. 8.2 ± 1.3% (P = 0.774), respectively. In men, insulin doses were 0.74 ± 0.21 vs. 0.71 ± 0.20 vs. 0.68 ± 0.23 IU · kg⁻¹ · 24 h⁻¹ (P = 0.003). In both sexes, sedentary patients had lower eGDRs than active patients [median (interquartile range) 5.5 (4.0-8.2) vs. 6.8 (4.7-8.8) vs. 6.7 (4.6-8.6) mg · kg⁻¹ · min⁻¹; P < 0.01 for sedentary vs. others]. Age, obesity, smoking, insulin dose, social class, diabetic nephropathy, or cardiovascular disease did not explain the results. CONCLUSIONS:--Low levels of LTPA were associated with poor glycemic control in type 1 diabetic women. Men seem to use less insulin when physically active. Increased LTPA levels were associated with increased estimated insulin sensitivity. Longitudinal studies are needed to further clarify the effects of LTPA on type 1 diabetes.</description><identifier>ISSN: 0149-5992</identifier><identifier>EISSN: 1935-5548</identifier><identifier>DOI: 10.2337/diacare.28.4.777</identifier><identifier>PMID: 15793172</identifier><identifier>CODEN: DICAD2</identifier><language>eng</language><publisher>Alexandria, VA: American Diabetes Association</publisher><subject>Adult ; Biological and medical sciences ; blood glucose ; Blood Glucose - metabolism ; Cross-Sectional Studies ; Diabetes ; Diabetes Mellitus, Type 1 - blood ; Diabetes Mellitus, Type 1 - physiopathology ; Diabetes. Impaired glucose tolerance ; Diabetic Angiopathies - epidemiology ; Diabetic Nephropathies - epidemiology ; Diabetic Retinopathy - epidemiology ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Evaluation ; Exercise ; Female ; Finland ; Glucose ; Glycated Hemoglobin A - analysis ; glycemic control ; Glycemic index ; hormone supplements ; Humans ; Insulin ; insulin resistance ; insulin-dependent diabetes mellitus ; Leisure ; Leisure Activities ; Life Style ; Male ; Medical sciences ; physical activity ; recreation ; Reproducibility of Results ; Sex Characteristics ; Surveys and Questionnaires ; Type 1 diabetes ; women</subject><ispartof>Diabetes care, 2005-04, Vol.28 (4), p.777-782</ispartof><rights>2005 INIST-CNRS</rights><rights>COPYRIGHT 2005 American Diabetes Association</rights><rights>Copyright American Diabetes Association Apr 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16658043$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15793172$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wadén, Johan</creatorcontrib><creatorcontrib>Tikkanen, Heikki</creatorcontrib><creatorcontrib>Forsblom, Carol</creatorcontrib><creatorcontrib>Fagerudd, Johan</creatorcontrib><creatorcontrib>Pettersson-Fernholm, Kim</creatorcontrib><creatorcontrib>Lakka, Timo</creatorcontrib><creatorcontrib>Riska, Mikael</creatorcontrib><creatorcontrib>Groop, Per-Henrik</creatorcontrib><creatorcontrib>FinnDiane Study Group</creatorcontrib><title>Leisure Time Physical Activity Is Associated With Poor Glycemic Control in Type 1 Diabetic Women: The FinnDiane study</title><title>Diabetes care</title><addtitle>Diabetes Care</addtitle><description>OBJECTIVE:--We studied the association between leisure time physical activity (LTPA) and glycemic control, insulin dose, and estimated glucose disposal rate (eGDR) in type 1 diabetes. RESEARCH DESIGN AND METHODS--This is a cross-sectional study of 1,030 type 1 diabetic patients participating in the Finnish Diabetic Nephropathy Study, a nationwide multicenter study. LTPA was assessed by a validated 12-month questionnaire and expressed in metabolic equivalent (MET) units. Patients were grouped as sedentary (LTPA <10 MET h/week, n = 247), moderately active (LTPA 10-40 MET h/week, n = 568), and active (LTPA >40 MET h/week, n = 215). Outcome measures were HbA[subscript 1c], insulin dose, and eGDR (estimate of insulin sensitivity based on waist-to-hip ratio, hypertension, and HbA[subscript 1c]). RESULTS:--LTPA correlated with HbA[subscript 1c] in women (r = -0.12, P = 0.007) but not in men (r = -0.03, P = 0.592). Sedentary women had higher HbA[subscript 1c] than moderately active and active women: 8.8 ± 1.4% vs. 8.3 ± 1.4% vs. 8.3 ± 1.4% (P = 0.004), whereas HbA[subscript 1c] in men was 8.4 ± 1.3% vs. 8.2 ± 1.4% vs. 8.2 ± 1.3% (P = 0.774), respectively. In men, insulin doses were 0.74 ± 0.21 vs. 0.71 ± 0.20 vs. 0.68 ± 0.23 IU · kg⁻¹ · 24 h⁻¹ (P = 0.003). In both sexes, sedentary patients had lower eGDRs than active patients [median (interquartile range) 5.5 (4.0-8.2) vs. 6.8 (4.7-8.8) vs. 6.7 (4.6-8.6) mg · kg⁻¹ · min⁻¹; P < 0.01 for sedentary vs. others]. Age, obesity, smoking, insulin dose, social class, diabetic nephropathy, or cardiovascular disease did not explain the results. CONCLUSIONS:--Low levels of LTPA were associated with poor glycemic control in type 1 diabetic women. Men seem to use less insulin when physically active. Increased LTPA levels were associated with increased estimated insulin sensitivity. Longitudinal studies are needed to further clarify the effects of LTPA on type 1 diabetes.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>blood glucose</subject><subject>Blood Glucose - metabolism</subject><subject>Cross-Sectional Studies</subject><subject>Diabetes</subject><subject>Diabetes Mellitus, Type 1 - blood</subject><subject>Diabetes Mellitus, Type 1 - physiopathology</subject><subject>Diabetes. Impaired glucose tolerance</subject><subject>Diabetic Angiopathies - epidemiology</subject><subject>Diabetic Nephropathies - epidemiology</subject><subject>Diabetic Retinopathy - epidemiology</subject><subject>Endocrine pancreas. Apud cells (diseases)</subject><subject>Endocrinopathies</subject><subject>Evaluation</subject><subject>Exercise</subject><subject>Female</subject><subject>Finland</subject><subject>Glucose</subject><subject>Glycated Hemoglobin A - analysis</subject><subject>glycemic control</subject><subject>Glycemic index</subject><subject>hormone supplements</subject><subject>Humans</subject><subject>Insulin</subject><subject>insulin resistance</subject><subject>insulin-dependent diabetes mellitus</subject><subject>Leisure</subject><subject>Leisure Activities</subject><subject>Life Style</subject><subject>Male</subject><subject>Medical sciences</subject><subject>physical activity</subject><subject>recreation</subject><subject>Reproducibility of Results</subject><subject>Sex Characteristics</subject><subject>Surveys and Questionnaires</subject><subject>Type 1 diabetes</subject><subject>women</subject><issn>0149-5992</issn><issn>1935-5548</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpt0c-LEzEUB_BBFLeu3j1pEPQ2NZn89laquy4UXLDLHoc089JmmUlqMiPMf2-WVgRZ3iHw8smXR15VvSV42VAqP3feWJNg2aglW0opn1ULoimvOWfqebXAhOmaa91cVK9yfsAYM6bUy-qCcKkpkc2imjbg85QAbf0A6PYwZ29Nj1Z29L_9OKObjFY5R-vNCB269-MB3caY0HU_Wxi8ResYxhR75APazkdABH31ZgdjubqPA4QvaHsAdOVDKP0AKI9TN7-uXjjTZ3hzPi-ru6tv2_X3evPj-ma92tSOCjnWVHc7gY3VeOe4xliCopJKQqXljkkuGHVWgVa2Y6RzVjjsgAqgGjRm2NHL6tMp95jirwny2A4-W-j7MkmccitKBuVCFPjhP_gQpxTKbG3TUEyVJKSg-oT2pofWBxfHZOweAiTTxwDOl_aK0FKKcVr88glfqnv8uScfvDtPMe0G6Npj8oNJc_t3XQV8PAOTy5pcMsH6_M8JwRVmj0HvT86Z2Jp9KubuZ4MJxVgr3XBC_wAxC6wj</recordid><startdate>20050401</startdate><enddate>20050401</enddate><creator>Wadén, Johan</creator><creator>Tikkanen, Heikki</creator><creator>Forsblom, Carol</creator><creator>Fagerudd, Johan</creator><creator>Pettersson-Fernholm, Kim</creator><creator>Lakka, Timo</creator><creator>Riska, Mikael</creator><creator>Groop, Per-Henrik</creator><general>American Diabetes Association</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7RV</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0K</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>20050401</creationdate><title>Leisure Time Physical Activity Is Associated With Poor Glycemic Control in Type 1 Diabetic Women: The FinnDiane study</title><author>Wadén, Johan ; Tikkanen, Heikki ; Forsblom, Carol ; Fagerudd, Johan ; Pettersson-Fernholm, Kim ; Lakka, Timo ; Riska, Mikael ; Groop, Per-Henrik</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-f367t-39db60ac90bf59007e83737137c5f475643fc8e98cd41dfc6f0fe36e39e9040f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>blood glucose</topic><topic>Blood Glucose - metabolism</topic><topic>Cross-Sectional Studies</topic><topic>Diabetes</topic><topic>Diabetes Mellitus, Type 1 - blood</topic><topic>Diabetes Mellitus, Type 1 - physiopathology</topic><topic>Diabetes. Impaired glucose tolerance</topic><topic>Diabetic Angiopathies - epidemiology</topic><topic>Diabetic Nephropathies - epidemiology</topic><topic>Diabetic Retinopathy - epidemiology</topic><topic>Endocrine pancreas. Apud cells (diseases)</topic><topic>Endocrinopathies</topic><topic>Evaluation</topic><topic>Exercise</topic><topic>Female</topic><topic>Finland</topic><topic>Glucose</topic><topic>Glycated Hemoglobin A - analysis</topic><topic>glycemic control</topic><topic>Glycemic index</topic><topic>hormone supplements</topic><topic>Humans</topic><topic>Insulin</topic><topic>insulin resistance</topic><topic>insulin-dependent diabetes mellitus</topic><topic>Leisure</topic><topic>Leisure Activities</topic><topic>Life Style</topic><topic>Male</topic><topic>Medical sciences</topic><topic>physical activity</topic><topic>recreation</topic><topic>Reproducibility of Results</topic><topic>Sex Characteristics</topic><topic>Surveys and Questionnaires</topic><topic>Type 1 diabetes</topic><topic>women</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wadén, Johan</creatorcontrib><creatorcontrib>Tikkanen, Heikki</creatorcontrib><creatorcontrib>Forsblom, Carol</creatorcontrib><creatorcontrib>Fagerudd, Johan</creatorcontrib><creatorcontrib>Pettersson-Fernholm, Kim</creatorcontrib><creatorcontrib>Lakka, Timo</creatorcontrib><creatorcontrib>Riska, Mikael</creatorcontrib><creatorcontrib>Groop, Per-Henrik</creatorcontrib><creatorcontrib>FinnDiane Study Group</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Agricultural Science Database</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Diabetes care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wadén, Johan</au><au>Tikkanen, Heikki</au><au>Forsblom, Carol</au><au>Fagerudd, Johan</au><au>Pettersson-Fernholm, Kim</au><au>Lakka, Timo</au><au>Riska, Mikael</au><au>Groop, Per-Henrik</au><aucorp>FinnDiane Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Leisure Time Physical Activity Is Associated With Poor Glycemic Control in Type 1 Diabetic Women: The FinnDiane study</atitle><jtitle>Diabetes care</jtitle><addtitle>Diabetes Care</addtitle><date>2005-04-01</date><risdate>2005</risdate><volume>28</volume><issue>4</issue><spage>777</spage><epage>782</epage><pages>777-782</pages><issn>0149-5992</issn><eissn>1935-5548</eissn><coden>DICAD2</coden><abstract>OBJECTIVE:--We studied the association between leisure time physical activity (LTPA) and glycemic control, insulin dose, and estimated glucose disposal rate (eGDR) in type 1 diabetes. RESEARCH DESIGN AND METHODS--This is a cross-sectional study of 1,030 type 1 diabetic patients participating in the Finnish Diabetic Nephropathy Study, a nationwide multicenter study. LTPA was assessed by a validated 12-month questionnaire and expressed in metabolic equivalent (MET) units. Patients were grouped as sedentary (LTPA <10 MET h/week, n = 247), moderately active (LTPA 10-40 MET h/week, n = 568), and active (LTPA >40 MET h/week, n = 215). Outcome measures were HbA[subscript 1c], insulin dose, and eGDR (estimate of insulin sensitivity based on waist-to-hip ratio, hypertension, and HbA[subscript 1c]). RESULTS:--LTPA correlated with HbA[subscript 1c] in women (r = -0.12, P = 0.007) but not in men (r = -0.03, P = 0.592). Sedentary women had higher HbA[subscript 1c] than moderately active and active women: 8.8 ± 1.4% vs. 8.3 ± 1.4% vs. 8.3 ± 1.4% (P = 0.004), whereas HbA[subscript 1c] in men was 8.4 ± 1.3% vs. 8.2 ± 1.4% vs. 8.2 ± 1.3% (P = 0.774), respectively. In men, insulin doses were 0.74 ± 0.21 vs. 0.71 ± 0.20 vs. 0.68 ± 0.23 IU · kg⁻¹ · 24 h⁻¹ (P = 0.003). In both sexes, sedentary patients had lower eGDRs than active patients [median (interquartile range) 5.5 (4.0-8.2) vs. 6.8 (4.7-8.8) vs. 6.7 (4.6-8.6) mg · kg⁻¹ · min⁻¹; P < 0.01 for sedentary vs. others]. Age, obesity, smoking, insulin dose, social class, diabetic nephropathy, or cardiovascular disease did not explain the results. CONCLUSIONS:--Low levels of LTPA were associated with poor glycemic control in type 1 diabetic women. Men seem to use less insulin when physically active. Increased LTPA levels were associated with increased estimated insulin sensitivity. Longitudinal studies are needed to further clarify the effects of LTPA on type 1 diabetes.</abstract><cop>Alexandria, VA</cop><pub>American Diabetes Association</pub><pmid>15793172</pmid><doi>10.2337/diacare.28.4.777</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0149-5992 |
| ispartof | Diabetes care, 2005-04, Vol.28 (4), p.777-782 |
| issn | 0149-5992 1935-5548 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67563566 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Biological and medical sciences blood glucose Blood Glucose - metabolism Cross-Sectional Studies Diabetes Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - physiopathology Diabetes. Impaired glucose tolerance Diabetic Angiopathies - epidemiology Diabetic Nephropathies - epidemiology Diabetic Retinopathy - epidemiology Endocrine pancreas. Apud cells (diseases) Endocrinopathies Evaluation Exercise Female Finland Glucose Glycated Hemoglobin A - analysis glycemic control Glycemic index hormone supplements Humans Insulin insulin resistance insulin-dependent diabetes mellitus Leisure Leisure Activities Life Style Male Medical sciences physical activity recreation Reproducibility of Results Sex Characteristics Surveys and Questionnaires Type 1 diabetes women |
| title | Leisure Time Physical Activity Is Associated With Poor Glycemic Control in Type 1 Diabetic Women: The FinnDiane study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T17%3A11%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Leisure%20Time%20Physical%20Activity%20Is%20Associated%20With%20Poor%20Glycemic%20Control%20in%20Type%201%20Diabetic%20Women:%20The%20FinnDiane%20study&rft.jtitle=Diabetes%20care&rft.au=Wade%CC%81n,%20Johan&rft.aucorp=FinnDiane%20Study%20Group&rft.date=2005-04-01&rft.volume=28&rft.issue=4&rft.spage=777&rft.epage=782&rft.pages=777-782&rft.issn=0149-5992&rft.eissn=1935-5548&rft.coden=DICAD2&rft_id=info:doi/10.2337/diacare.28.4.777&rft_dat=%3Cgale_proqu%3EA131318453%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=223038711&rft_id=info:pmid/15793172&rft_galeid=A131318453&rfr_iscdi=true |