Synthesis and Biological Evaluation of a Natural Ester Sintenin and Its Synthetic Analogues

Synthesis of 3-(3,4-dimethoxyphenyl)propyl-3-(3,4-dimethoxyphenyl) propanoate (18), a cytotoxic natural ester, was carried out by a convenient synthetic path with a total yield of 49%. Sixteen of its analogues (19−34) were also prepared. Seventeen unsaturated derivatives of 18, compounds 1−17, were...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2005-03, Vol.68 (3), p.342-348
Hauptverfasser:	Hu, Li Hong, Zou, Hong Bin, Gong, Jing Xu, Li, Hai Bo, Yang, Lei Xiang, Cheng, Wei, Zhou, Chang Xin, Bai, Hua, Guéritte, Françoise, Zhao, Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-glucosidase anticarcinogenic activity Antineoplastic agents Antineoplastic Agents - chemical synthesis Antineoplastic Agents - pharmacology Biological and medical sciences cell lines chemical reactions chemical structure cytotoxicity Drug Screening Assays, Antitumor enzyme inhibition esters Esters - chemical synthesis Esters - pharmacology General aspects Humans Medical sciences Molecular Structure Pharmacology. Drug treatments phenolic compounds phytochemicals Piper sintenense Piperaceae propionates Propionates - chemistry Propionates - isolation & purification Propionates - pharmacology sintenin Structure-Activity Relationship Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!