Molecular case report: IgvH analysis in acute humoral and cellular liver allograft rejection suggests a selected accumulation of effector B cells and plasma cells

Acute cellular (CLR) and humoral liver allograft rejection (HLR) are the most important immunological obstacles to successful liver transplantation. In HLR, serum antibodies play the central pathogenetic role. In CLR, CD3+ T lymphocytes drive the destructive immune response. Although CLR and HLR sho...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2005-03, Vol.446 (3), p.325-332
Hauptverfasser:	MOELLER, Johannes, KRUKEMEYER, Manfred G, MORAWIETZ, Lars, SCHMEDING, Max, DANKOF, Anja, NEUMANN, Ulf, KRENN, Veit, BEREK, Claudia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amino Acid Sequence Antigens Base Sequence Biological and medical sciences Female Graft Rejection - immunology Graft Rejection - pathology Humans Immune response Immune system Immunoglobulin Variable Region - genetics Immunohistochemistry Investigative techniques, diagnostic techniques (general aspects) Liver Liver transplantation Liver Transplantation - immunology Liver Transplantation - pathology Lymphocytes Male Medical sciences Middle Aged Molecular Sequence Data Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Plasma Cells - immunology Reverse Transcriptase Polymerase Chain Reaction T-Lymphocytes - immunology Transplantation, Homologous
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