FGF2 modulates the voltage-dependent K+ current and changes excitability of rat dentate gyrus granule cells

Fibroblast growth factor 2 (FGF2) is involved in hippocampus-dependent learning. In this study, the effects of FGF2 on the excitability were investigated in granule cells of rat dentate gyrus. Hippocampal slices were used to perform patch clamp recordings in granule cells. Extracellularly applied FG...

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Veröffentlicht in:	Neuroscience letters 2009-09, Vol.462 (3), p.203-206
Hauptverfasser:	Cuppini, Carla, Ambrogini, Patrizia, Lattanzi, Davide, Ciuffoli, Stefano, Cuppini, Riccardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Animals Biological and medical sciences Cell excitability Dentate gyrus Dentate Gyrus - physiology FGF2 Fibroblast Growth Factor 2 - physiology Fundamental and applied biological sciences. Psychology In Vitro Techniques K+ current Male Neurons - physiology Patch-Clamp Techniques Potassium Channels, Voltage-Gated - physiology Rat Rats Rats, Sprague-Dawley Vertebrates: nervous system and sense organs
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