Towards Solid Tumor Treatment by Nanosecond Pulsed Electric Fields

Local and drug-free solid tumor ablation by large nanosecond pulsed electric fields leads to supra-electroporation of all cellular membranes and has been observed to trigger nonthermal cell death by apoptosis. To establish pore-based effects as the underlying mechanism inducing apoptosis, we use a m...

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Veröffentlicht in:	Technology in cancer research & treatment 2009-08, Vol.8 (4), p.289-306
Hauptverfasser:	Esser, Axel T., Smith, Kyle C., Gowrishankar, T. R., Weaver, James C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Electroporation Humans Medical sciences Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasms - therapy Other treatments Temperature Treatment. General aspects Tumors
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