Premedication in children: hypnosis versus midazolam

Summary Background:  The main objectives of premedication in children are to facilitate the separation from the parents, to reduce preoperative anxiety, to smooth the induction of anesthesia and to lower the risk of postoperative behavioral disorders. The most common technique is sedative premedicat...

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Veröffentlicht in:Pediatric anesthesia 2005-04, Vol.15 (4), p.275-281
Hauptverfasser: CALIPEL, SÉVERINE, LUCAS-POLOMENI, MARIE-MADELEINE, WODEY, ERIC, ECOFFEY, CLAUDE
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container_issue 4
container_start_page 275
container_title Pediatric anesthesia
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creator CALIPEL, SÉVERINE
LUCAS-POLOMENI, MARIE-MADELEINE
WODEY, ERIC
ECOFFEY, CLAUDE
description Summary Background:  The main objectives of premedication in children are to facilitate the separation from the parents, to reduce preoperative anxiety, to smooth the induction of anesthesia and to lower the risk of postoperative behavioral disorders. The most common technique is sedative premedication with midazolam. Hypnosis enables a state of relaxation to be achieved and has never been evaluated as a premedication technique. The aim of the present study was to evaluate the efficacy of hypnosis on anxiety and perioperative behavioral disorders versus midazolam. Methods:  Fifty children from 2 to 11 years of age were randomized into two groups: group H received hypnosis as premedication; group M were given 0.5 mg·kg−1 midazolam orally, 30 min before surgery. Preoperative anxiety was evaluated using the Modified Yale Preoperative Anxiety Scale (mYPAS) score when arriving in the department (T1), when entering the operating room (T2), and when fitting the facemask (T3). Postoperative behavioral disorders were evaluated using the Posthospitalization Behavioral Questionnaire (PHBQ) at days 1, 7 and 14. Results:  The two groups showed no significant difference preoperatively with the PHBQ: (M) 21 (17–25) vs (H) 20 (8–25) and mYPAS score: (M) 28 (23–75) vs (H) 23 (23–78). The number of anxious children was less during induction of anesthesia in the hypnosis group (T3: 39% vs 68%) (P 
doi_str_mv 10.1111/j.1460-9592.2004.01514.x
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The most common technique is sedative premedication with midazolam. Hypnosis enables a state of relaxation to be achieved and has never been evaluated as a premedication technique. The aim of the present study was to evaluate the efficacy of hypnosis on anxiety and perioperative behavioral disorders versus midazolam. Methods:  Fifty children from 2 to 11 years of age were randomized into two groups: group H received hypnosis as premedication; group M were given 0.5 mg·kg−1 midazolam orally, 30 min before surgery. Preoperative anxiety was evaluated using the Modified Yale Preoperative Anxiety Scale (mYPAS) score when arriving in the department (T1), when entering the operating room (T2), and when fitting the facemask (T3). Postoperative behavioral disorders were evaluated using the Posthospitalization Behavioral Questionnaire (PHBQ) at days 1, 7 and 14. Results:  The two groups showed no significant difference preoperatively with the PHBQ: (M) 21 (17–25) vs (H) 20 (8–25) and mYPAS score: (M) 28 (23–75) vs (H) 23 (23–78). The number of anxious children was less during induction of anesthesia in the hypnosis group (T3: 39% vs 68%) (P &lt; 0.05). Postoperatively, hypnosis reduced the frequency of behavior disorders approximately by half on day 1 (30% vs 62%) and day 7 (26% vs 59%). Conclusions:  Hypnosis seems effective as premedication in children scheduled for surgery. It alleviates preoperative anxiety, especially during induction of anesthesia and reduces behavioral disorders during the first postoperative week.</description><identifier>ISSN: 1155-5645</identifier><identifier>EISSN: 1460-9592</identifier><identifier>DOI: 10.1111/j.1460-9592.2004.01514.x</identifier><identifier>PMID: 15787917</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Ltd</publisher><subject>Abdomen - surgery ; Anesthesia ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Anxiety - psychology ; Behavior - drug effects ; Biological and medical sciences ; Child ; Child, Preschool ; children ; Double-Blind Method ; Female ; Humans ; Hypnosis ; Hypnotics and Sedatives ; Male ; Medical sciences ; Midazolam ; postoperative behavioral disorders ; Postoperative Complications - epidemiology ; Postoperative Complications - psychology ; Preanesthetic Medication ; premedication ; preoperative anxiety ; Psychiatric Status Rating Scales</subject><ispartof>Pediatric anesthesia, 2005-04, Vol.15 (4), p.275-281</ispartof><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5014-53be44f88d193a3c2f76c3a987bfc80bd613f8bf60133b97fce2532957c7fe103</citedby><cites>FETCH-LOGICAL-c5014-53be44f88d193a3c2f76c3a987bfc80bd613f8bf60133b97fce2532957c7fe103</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1460-9592.2004.01514.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1460-9592.2004.01514.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=16603905$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15787917$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>CALIPEL, SÉVERINE</creatorcontrib><creatorcontrib>LUCAS-POLOMENI, MARIE-MADELEINE</creatorcontrib><creatorcontrib>WODEY, ERIC</creatorcontrib><creatorcontrib>ECOFFEY, CLAUDE</creatorcontrib><title>Premedication in children: hypnosis versus midazolam</title><title>Pediatric anesthesia</title><addtitle>Paediatr Anaesth</addtitle><description>Summary Background:  The main objectives of premedication in children are to facilitate the separation from the parents, to reduce preoperative anxiety, to smooth the induction of anesthesia and to lower the risk of postoperative behavioral disorders. The most common technique is sedative premedication with midazolam. Hypnosis enables a state of relaxation to be achieved and has never been evaluated as a premedication technique. The aim of the present study was to evaluate the efficacy of hypnosis on anxiety and perioperative behavioral disorders versus midazolam. Methods:  Fifty children from 2 to 11 years of age were randomized into two groups: group H received hypnosis as premedication; group M were given 0.5 mg·kg−1 midazolam orally, 30 min before surgery. Preoperative anxiety was evaluated using the Modified Yale Preoperative Anxiety Scale (mYPAS) score when arriving in the department (T1), when entering the operating room (T2), and when fitting the facemask (T3). Postoperative behavioral disorders were evaluated using the Posthospitalization Behavioral Questionnaire (PHBQ) at days 1, 7 and 14. Results:  The two groups showed no significant difference preoperatively with the PHBQ: (M) 21 (17–25) vs (H) 20 (8–25) and mYPAS score: (M) 28 (23–75) vs (H) 23 (23–78). The number of anxious children was less during induction of anesthesia in the hypnosis group (T3: 39% vs 68%) (P &lt; 0.05). Postoperatively, hypnosis reduced the frequency of behavior disorders approximately by half on day 1 (30% vs 62%) and day 7 (26% vs 59%). Conclusions:  Hypnosis seems effective as premedication in children scheduled for surgery. It alleviates preoperative anxiety, especially during induction of anesthesia and reduces behavioral disorders during the first postoperative week.</description><subject>Abdomen - surgery</subject><subject>Anesthesia</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Anxiety - psychology</subject><subject>Behavior - drug effects</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>children</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Humans</subject><subject>Hypnosis</subject><subject>Hypnotics and Sedatives</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Midazolam</subject><subject>postoperative behavioral disorders</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative Complications - psychology</subject><subject>Preanesthetic Medication</subject><subject>premedication</subject><subject>preoperative anxiety</subject><subject>Psychiatric Status Rating Scales</subject><issn>1155-5645</issn><issn>1460-9592</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMlOwzAQhi0EYn8FlAvcEux4i5E4oLIUqSqIRRwtx7GFS5Zit9Dy9Di0giu-zEj-fnvmAyBBMEPxnE4yRBhMBRV5lkNIMogoItliA-z-XmzGHlGaUkboDtgLYQIhwjnLt8EOorzgAvFdQO69aUzltJq5rk1cm-hXV1fetGfJ63LadsGF5MP4MA9J4yr11dWqOQBbVtXBHK7rPni-vnoaDNPR3c3t4GKUagoRSSkuDSG2KCoksMI6t5xprETBS6sLWFYMYVuUlsW5cCm41SanOBeUa24NgngfnKzenfrufW7CTDYuaFPXqjXdPEjGKRE45xEsVqD2XQjeWDn1rlF-KRGUvTE5kb0Y2YuRvTH5Y0wuYvRo_ce8jCL-gmtFETheAypoVVuvWu3CH8cYxALSyJ2vuE9Xm-W_B5D3F-O-i_l0lXdhZha_eeXf4p6YU_kyvpFPj8Mhf7yE8gF_A1pslTk</recordid><startdate>200504</startdate><enddate>200504</enddate><creator>CALIPEL, SÉVERINE</creator><creator>LUCAS-POLOMENI, MARIE-MADELEINE</creator><creator>WODEY, ERIC</creator><creator>ECOFFEY, CLAUDE</creator><general>Blackwell Science Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200504</creationdate><title>Premedication in children: hypnosis versus midazolam</title><author>CALIPEL, SÉVERINE ; LUCAS-POLOMENI, MARIE-MADELEINE ; WODEY, ERIC ; ECOFFEY, CLAUDE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5014-53be44f88d193a3c2f76c3a987bfc80bd613f8bf60133b97fce2532957c7fe103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Abdomen - surgery</topic><topic>Anesthesia</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Anxiety - psychology</topic><topic>Behavior - drug effects</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>children</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Humans</topic><topic>Hypnosis</topic><topic>Hypnotics and Sedatives</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Midazolam</topic><topic>postoperative behavioral disorders</topic><topic>Postoperative Complications - epidemiology</topic><topic>Postoperative Complications - psychology</topic><topic>Preanesthetic Medication</topic><topic>premedication</topic><topic>preoperative anxiety</topic><topic>Psychiatric Status Rating Scales</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CALIPEL, SÉVERINE</creatorcontrib><creatorcontrib>LUCAS-POLOMENI, MARIE-MADELEINE</creatorcontrib><creatorcontrib>WODEY, ERIC</creatorcontrib><creatorcontrib>ECOFFEY, CLAUDE</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>CALIPEL, SÉVERINE</au><au>LUCAS-POLOMENI, MARIE-MADELEINE</au><au>WODEY, ERIC</au><au>ECOFFEY, CLAUDE</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Premedication in children: hypnosis versus midazolam</atitle><jtitle>Pediatric anesthesia</jtitle><addtitle>Paediatr Anaesth</addtitle><date>2005-04</date><risdate>2005</risdate><volume>15</volume><issue>4</issue><spage>275</spage><epage>281</epage><pages>275-281</pages><issn>1155-5645</issn><eissn>1460-9592</eissn><abstract>Summary Background:  The main objectives of premedication in children are to facilitate the separation from the parents, to reduce preoperative anxiety, to smooth the induction of anesthesia and to lower the risk of postoperative behavioral disorders. The most common technique is sedative premedication with midazolam. Hypnosis enables a state of relaxation to be achieved and has never been evaluated as a premedication technique. The aim of the present study was to evaluate the efficacy of hypnosis on anxiety and perioperative behavioral disorders versus midazolam. Methods:  Fifty children from 2 to 11 years of age were randomized into two groups: group H received hypnosis as premedication; group M were given 0.5 mg·kg−1 midazolam orally, 30 min before surgery. Preoperative anxiety was evaluated using the Modified Yale Preoperative Anxiety Scale (mYPAS) score when arriving in the department (T1), when entering the operating room (T2), and when fitting the facemask (T3). Postoperative behavioral disorders were evaluated using the Posthospitalization Behavioral Questionnaire (PHBQ) at days 1, 7 and 14. Results:  The two groups showed no significant difference preoperatively with the PHBQ: (M) 21 (17–25) vs (H) 20 (8–25) and mYPAS score: (M) 28 (23–75) vs (H) 23 (23–78). The number of anxious children was less during induction of anesthesia in the hypnosis group (T3: 39% vs 68%) (P &lt; 0.05). Postoperatively, hypnosis reduced the frequency of behavior disorders approximately by half on day 1 (30% vs 62%) and day 7 (26% vs 59%). Conclusions:  Hypnosis seems effective as premedication in children scheduled for surgery. It alleviates preoperative anxiety, especially during induction of anesthesia and reduces behavioral disorders during the first postoperative week.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>15787917</pmid><doi>10.1111/j.1460-9592.2004.01514.x</doi><tpages>7</tpages></addata></record>
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subjects Abdomen - surgery
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Anxiety - psychology
Behavior - drug effects
Biological and medical sciences
Child
Child, Preschool
children
Double-Blind Method
Female
Humans
Hypnosis
Hypnotics and Sedatives
Male
Medical sciences
Midazolam
postoperative behavioral disorders
Postoperative Complications - epidemiology
Postoperative Complications - psychology
Preanesthetic Medication
premedication
preoperative anxiety
Psychiatric Status Rating Scales
title Premedication in children: hypnosis versus midazolam
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