Long lasting immunity in chickens induced by a single shot of influenza vaccine prepared from inactivated non-pathogenic H5N1 virus particles against challenge with a highly pathogenic avian influenza virus

Abstract An influenza vaccine was prepared from inactivated whole particles of the non-pathogenic strain A/duck/Hokkaido/Vac-1/04 (H5N1) virus using an oil adjuvant containing anhydromannitol-octadecenoate-ether (AMOE). The vaccine was injected intramuscularly into five 4-week-old chickens, and 138...

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Veröffentlicht in:	Vaccine 2009-08, Vol.27 (38), p.5174-5177
Hauptverfasser:	Sasaki, Takashi, Kokumai, Norihide, Ohgitani, Toshiaki, Sakamoto, Ryuichi, Takikawa, Noriyasu, Lin, Zhifeng, Okamatsu, Masatoshi, Sakoda, Yoshihiro, Kida, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic Allergy and Immunology Animal vaccines Animals Antibodies, Viral - blood Antigens Applied microbiology Aquatic birds Atoms & subatomic particles Avian influenza vaccine Biological and medical sciences Chickens Chickens - immunology Chickens - virology Fundamental and applied biological sciences. Psychology H5 virus Hemagglutination Inhibition Tests - veterinary Influenza A Virus, H5N1 Subtype - immunology Influenza A Virus, H5N1 Subtype - pathogenicity Influenza in Birds - immunology Influenza in Birds - prevention & control Influenza Vaccines - immunology Lasting protective immunity Microbiology Miscellaneous Poultry Reassortant Viruses - immunology Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Veterinary medicine Virology Viruses
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