Survival of Endothelial Cells in vitro on Paclitaxel-loaded Coronary Stents

Coronary stents that are developed for use with balloon angioplasty are known to cause acute occlusion and long-term stenosis. It is likely that a controlled release of drugs at the site of stent implantation might inhibit the proliferation of vascular smooth muscle cells (VSMC) and reduce restenosi...

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Veröffentlicht in:	Journal of biomaterials applications 2005-04, Vol.19 (4), p.271-286
Hauptverfasser:	Prasad, C. Krishna, Resmi, K. R., Krishnan, Lissy K., Vaishnav, Rajesh
Format:	Artikel
Sprache:	eng
Schlagworte:	Angioplasty, Balloon, Coronary - instrumentation Apoptosis - drug effects Blood Vessel Prosthesis Cell Adhesion - drug effects Cell Proliferation - drug effects Cell Survival - drug effects Cells, Cultured Coated Materials, Biocompatible - administration & dosage Coated Materials, Biocompatible - chemistry Coronary Restenosis - prevention & control Delayed-Action Preparations - administration & dosage Delayed-Action Preparations - chemistry Endothelial Cells - cytology Endothelial Cells - drug effects Endothelial Cells - physiology Equipment Failure Analysis Graft Occlusion, Vascular - prevention & control Humans Materials Testing Paclitaxel - administration & dosage Paclitaxel - chemistry Stents
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