Human Papillomavirus Genotype Specificity of Hybrid Capture 2 Low-Risk Probe Cocktail
A genotyping study of 285 Hybrid Capture 2 low-risk probe cocktail-positive specimens showed cross-reactivity with several untargeted human papillomavirus genotypes. Cross-reactivity was often clinically beneficial due to the detection of untargeted low-risk genotypes. A total of 8.4% of positive re...
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Veröffentlicht in: | Journal of Clinical Microbiology 2009-08, Vol.47 (8), p.2611-2615 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A genotyping study of 285 Hybrid Capture 2 low-risk probe cocktail-positive specimens showed cross-reactivity with several untargeted human papillomavirus genotypes. Cross-reactivity was often clinically beneficial due to the detection of untargeted low-risk genotypes. A total of 8.4% of positive results, usually weak, were due to cross-reactivity with high-risk genotypes. Establishment of a gray zone is recommended. |
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ISSN: | 0095-1137 1098-660X |
DOI: | 10.1128/JCM.00278-09 |