Synthesis and biological evaluation of novel 1-(4-methoxyphenethyl)-1H-benzimidazole-5-carboxylic acid derivatives and their precursors as antileukemic agents

We report here the synthesis and preliminary evaluation of novel 1-(4-methoxyphenethyl)-1H-benzimidazole-5-carboxylic acid derivatives 6(a-k) and their precursors 5(a-k) as potential chemotherapeutic agents. In each case, the structures of the compounds were determined by FTIR, (1)H NMR and mass spe...

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Veröffentlicht in:Bioorganic & medicinal chemistry letters 2009-08, Vol.19 (16), p.4594-4600
Hauptverfasser: THIMME GOWDA, N. R, KAVITHA, C. V, CHIRUVELLA, Kishore K, JOY, Omana, RANGAPPA, Kanchugarakoppal S, RAGHAVAN, Sathees C
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