The Erythropoietin NeuroProtective Effect: Assessment in CABG Surgery (TENPEAKS) A Randomized, Double-Blind, Placebo Controlled, Proof-of-Concept Clinical Trial

Neurocognitive dysfunction complicates coronary artery bypass surgery. Erythropoietin may be neuroprotective. We sought to determine whether human recombinant erythropoietin would reduce the incidence of neurocognitive dysfunction after surgery. We randomly assigned 32 elective first-time coronary a...

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Veröffentlicht in:	Stroke (1970) 2009-08, Vol.40 (8), p.2769-2775
Hauptverfasser:	HALJAN, Gregory, MAITLAND, Andrew, BUCHAN, Alastair, ARORA, Rakesh C, KING, Michael, HAIGH, John, CULLETON, Bruce, FARIS, Peter, ZYGUN, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Cognition Disorders - epidemiology Cognition Disorders - etiology Cognition Disorders - prevention & control Coronary Artery Bypass - adverse effects Double-Blind Method Erythropoietin - therapeutic use Feasibility Studies Follow-Up Studies Humans Male Medical sciences Middle Aged Muscle Neurology Neuroprotective Agents - therapeutic use Pharmacology. Drug treatments Postoperative Complications - epidemiology Postoperative Complications - etiology Postoperative Complications - prevention & control Recombinant Proteins Vascular diseases and vascular malformations of the nervous system
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