Ligands for peroxisome proliferator-activated receptor gamma have potent antitumor effect against human renal cell carcinoma

To examine whether peroxisome proliferator-activated receptor gamma (PPARγ) is expressed in human renal cell carcinoma (RCC) cells, and whether activation of PPARγ by its ligands can have multiple antitumor effects on human RCC cells in vitro. We examined the expression of PPARγ in four human RCC ce...

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Veröffentlicht in:	Urology (Ridgewood, N.J.) N.J.), 2005-03, Vol.65 (3), p.594-599
Hauptverfasser:	Yuan, Jinyang, Takahashi, Atsushi, Masumori, Naoya, Uchida, Kohsuke, Hisasue, Shin-Ichi, Kitamura, Hiroshi, Itoh, Naoki, Tsukamoto, Taiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carcinoma, Renal Cell - drug therapy Carcinoma, Renal Cell - metabolism Cell Division - drug effects Dose-Response Relationship, Drug Humans Kidney Neoplasms - drug therapy Kidney Neoplasms - metabolism Kidneys Medical sciences Nephrology. Urinary tract diseases PPAR gamma - metabolism Prostaglandin D2 - analogs & derivatives Prostaglandin D2 - pharmacology Prostaglandin D2 - therapeutic use Retinoid X Receptor alpha - metabolism Thiazolidinediones - pharmacology Thiazolidinediones - therapeutic use Tumor Cells, Cultured Tumors of the urinary system
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