Comparative studies of Avipox-GM-CSF versus recombinant GM-CSF protein as immune adjuvants with different vaccine platforms

Granulocyte–macrophage colony-stimulating factor (GM-CSF) is a potent immune stimulant when administered with different vaccines. Optimal use of GM-CSF resides in its ability to act locally to stimulate the proliferation and maturation of professional antigen-presenting cells (APCs) (i.e., Langerhan...

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Veröffentlicht in:	Vaccine 2005-04, Vol.23 (22), p.2909-2921
Hauptverfasser:	Reali, E., Canter, D., Zeytin, H., Schlom, J., Greiner, J.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Applied microbiology Avipox-GM-CSF Avipoxvirus - genetics Biological and medical sciences Comparative studies Cytokines E coli Female Fundamental and applied biological sciences. Psychology Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage Granulocyte-Macrophage Colony-Stimulating Factor - blood Granulocyte-Macrophage Colony-Stimulating Factor - immunology Immune adjuvant Immune system Immunization Injection Injections Lymph nodes Medical research Mice Microbiology Peptides Poxvirus Proteins Recombinant Proteins - administration & dosage Recombinant Proteins - immunology Smallpox Studies T-Lymphocytes, Cytotoxic - immunology Tumors Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Viruses
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