Protection against a Malaria Challenge by Sporozoite Inoculation

The need for an effective malaria vaccine is great, and the current lead strategy undergoing advanced testing is based on the use of the circumsporozoite protein. In this early-stage investigation, the authors followed a different strategy, using an attenuated Plasmodium falciparum sporozoite vaccin...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2009-07, Vol.361 (5), p.468-477
Hauptverfasser:	Roestenberg, Meta, McCall, Matthew, Hopman, Joost, Wiersma, Jorien, Luty, Adrian J.F, van Gemert, Geert Jan, van de Vegte-Bolmer, Marga, van Schaijk, Ben, Teelen, Karina, Arens, Theo, Spaarman, Lopke, de Mast, Quirijn, Roeffen, Will, Snounou, Georges, Rénia, Laurent, van der Ven, Andre, Hermsen, Cornelus C, Sauerwein, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Anopheles - parasitology Antibodies, Protozoan - blood Antimalarials - therapeutic use Biological and medical sciences Biomarkers - blood Blood - parasitology Chloroquine - therapeutic use Double-Blind Method Gene expression General aspects HIV Human immunodeficiency virus Human protozoal diseases Humans Infectious diseases Interferon-gamma - biosynthesis Interleukin-2 - biosynthesis Malaria Malaria Vaccines - adverse effects Malaria Vaccines - immunology Malaria, Falciparum - immunology Malaria, Falciparum - parasitology Malaria, Falciparum - prevention & control Medical research Medical sciences Mosquitoes Parasitemia Parasitic diseases Plasmodium falciparum - immunology Plasmodium falciparum - isolation & purification Protozoal diseases Sporozoites - immunology T-Lymphocytes - immunology Tumor Necrosis Factor-alpha - biosynthesis Vaccines Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!