FTY720 Pharmacokinetics in Mild to Moderate Hepatic Impairment

The influence of mild and moderate hepatic impairment on FTY720 pharmacokinetics was assessed. The authors enrolled 32 subjects consisting of 8 with mild and 8 with moderate hepatic impairment based on Child‐Pugh criteria and 16 demographically matched control subjects. A single 1‐mg oral dose of FT...

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Veröffentlicht in:Journal of clinical pharmacology 2005-04, Vol.45 (4), p.446-452
Hauptverfasser: Kovarik, J. M., Schmouder, R. L., Serra, D., Wang, Y., Wiegand, H., Dilzer, S. C., Lasseter, K. C.
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Sprache:eng
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