Dissection of the Mitochondrial Import and Assembly Pathway for Human Tom40

Tom40 is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM complex), essential for protein import into mitochondria. Tom40 is synthesized in the cytosol and contains information for its mitochondrial targeting and assembly. A number of stable import intermediate...

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Veröffentlicht in:	The Journal of biological chemistry 2005-03, Vol.280 (12), p.11535-11543
Hauptverfasser:	Humphries, Adam D., Streimann, Illo C., Stojanovski, Diana, Johnston, Amelia J., Yano, Masato, Hoogenraad, Nicholas J., Ryan, Michael T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - physiology HSP90 Heat-Shock Proteins - physiology Humans Membrane Transport Proteins - chemistry Membrane Transport Proteins - metabolism Membrane Transport Proteins - physiology Mitochondria - metabolism Mitochondrial Proteins - physiology Protein Precursors - metabolism Protein Transport Receptors, Cell Surface - physiology
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