What is your diagnosis? Vertebral mass in a dog

: A 1‐year‐old, castrated male, mixed‐breed dog was presented for sporadic episodes of kyphosis, tremors, and vocalizing. On neurologic examination, the lesion was localized to spinal cord segments T3–L3. Magnetic resonance imaging of the spine showed an expansile mass occupying most of the ventral...

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Veröffentlicht in:Veterinary clinical pathology 2009-06, Vol.38 (2), p.257-260
Hauptverfasser: Khachatryan, Artashes R, Wills, Tamara B, Potter, Kathleen A
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creator Khachatryan, Artashes R
Wills, Tamara B
Potter, Kathleen A
description : A 1‐year‐old, castrated male, mixed‐breed dog was presented for sporadic episodes of kyphosis, tremors, and vocalizing. On neurologic examination, the lesion was localized to spinal cord segments T3–L3. Magnetic resonance imaging of the spine showed an expansile mass occupying most of the ventral aspect of the spinous process of T6. Fine‐needle aspirates of the mass were examined cytologically. A moderately cellular population of pleomorphic spindle cells and abundant mucinous matrix were observed. The cytologic diagnosis was spindle cell neoplasia, with myxosarcoma and fibrosarcoma as the primary differential diagnoses. The dog was euthanized. Histopathologic evaluation of the mass and surrounding tissue confirmed a low‐grade spindle cell sarcoma, with severe compressive myelopathy and mild neutrophilic inflammation. The neoplastic cells stained positive for mucopolysaccharides with Alcian blue, resulting in a final diagnosis of low‐grade (grade 1) myxosarcoma. Fine‐needle aspiration was useful in making a preliminary diagnosis of myxosarcoma in this case. Myxosarcoma should be included in the differential diagnosis for a vertebral mass in a young dog.
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Histopathologic evaluation of the mass and surrounding tissue confirmed a low‐grade spindle cell sarcoma, with severe compressive myelopathy and mild neutrophilic inflammation. The neoplastic cells stained positive for mucopolysaccharides with Alcian blue, resulting in a final diagnosis of low‐grade (grade 1) myxosarcoma. Fine‐needle aspiration was useful in making a preliminary diagnosis of myxosarcoma in this case. 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Vertebral mass in a dog</title><title>Veterinary clinical pathology</title><addtitle>Vet Clin Pathol</addtitle><description>: A 1‐year‐old, castrated male, mixed‐breed dog was presented for sporadic episodes of kyphosis, tremors, and vocalizing. On neurologic examination, the lesion was localized to spinal cord segments T3–L3. Magnetic resonance imaging of the spine showed an expansile mass occupying most of the ventral aspect of the spinous process of T6. Fine‐needle aspirates of the mass were examined cytologically. A moderately cellular population of pleomorphic spindle cells and abundant mucinous matrix were observed. The cytologic diagnosis was spindle cell neoplasia, with myxosarcoma and fibrosarcoma as the primary differential diagnoses. The dog was euthanized. Histopathologic evaluation of the mass and surrounding tissue confirmed a low‐grade spindle cell sarcoma, with severe compressive myelopathy and mild neutrophilic inflammation. The neoplastic cells stained positive for mucopolysaccharides with Alcian blue, resulting in a final diagnosis of low‐grade (grade 1) myxosarcoma. Fine‐needle aspiration was useful in making a preliminary diagnosis of myxosarcoma in this case. 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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects animal pathology
Animals
case studies
cell biology
central nervous system diseases
complications
Cytology
differential staining
disease diagnosis
dog diseases
Dog Diseases - diagnosis
Dog Diseases - pathology
Dogs
fine-needle aspiration
fine‐needle aspirate
histopathology
image analysis
magnetic resonance imaging
Male
metastasis
mucopolysaccharide
musculoskeletal diseases
myxosarcoma
Myxosarcoma - diagnosis
Myxosarcoma - pathology
Myxosarcoma - veterinary
neuropathy
sarcoma
signs and symptoms (animals and humans)
spinal cord
Spinal Cord Neoplasms - diagnosis
Spinal Cord Neoplasms - pathology
Spinal Cord Neoplasms - veterinary
spine
title What is your diagnosis? Vertebral mass in a dog
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