What is your diagnosis? Vertebral mass in a dog
: A 1‐year‐old, castrated male, mixed‐breed dog was presented for sporadic episodes of kyphosis, tremors, and vocalizing. On neurologic examination, the lesion was localized to spinal cord segments T3–L3. Magnetic resonance imaging of the spine showed an expansile mass occupying most of the ventral...
Gespeichert in:
Veröffentlicht in: | Veterinary clinical pathology 2009-06, Vol.38 (2), p.257-260 |
---|---|
Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 260 |
---|---|
container_issue | 2 |
container_start_page | 257 |
container_title | Veterinary clinical pathology |
container_volume | 38 |
creator | Khachatryan, Artashes R Wills, Tamara B Potter, Kathleen A |
description | : A 1‐year‐old, castrated male, mixed‐breed dog was presented for sporadic episodes of kyphosis, tremors, and vocalizing. On neurologic examination, the lesion was localized to spinal cord segments T3–L3. Magnetic resonance imaging of the spine showed an expansile mass occupying most of the ventral aspect of the spinous process of T6. Fine‐needle aspirates of the mass were examined cytologically. A moderately cellular population of pleomorphic spindle cells and abundant mucinous matrix were observed. The cytologic diagnosis was spindle cell neoplasia, with myxosarcoma and fibrosarcoma as the primary differential diagnoses. The dog was euthanized. Histopathologic evaluation of the mass and surrounding tissue confirmed a low‐grade spindle cell sarcoma, with severe compressive myelopathy and mild neutrophilic inflammation. The neoplastic cells stained positive for mucopolysaccharides with Alcian blue, resulting in a final diagnosis of low‐grade (grade 1) myxosarcoma. Fine‐needle aspiration was useful in making a preliminary diagnosis of myxosarcoma in this case. Myxosarcoma should be included in the differential diagnosis for a vertebral mass in a young dog. |
doi_str_mv | 10.1111/j.1939-165X.2009.00116.x |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67529315</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67529315</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4566-ed7f87dd3376b65781a02aaccb93b0c9925306d3a003c672ac7ffdae895177ba3</originalsourceid><addsrcrecordid>eNqNkE1Lw0AQhhdRbK3-Bd2Tt6T70d3NgiBS_IKCgrZ6WybZTU1Jm7rbYPvvTUzRq3OZYeZ9Z4YHIUxJTJsYLmKquY6oFO8xI0THhFAq4-0B6v8ODlGfMCUiyRPWQychLAjhomkdox7VI02E1H00fPuADS4C3lW1x7aA-aoKRbjGM-c3LvVQ4iWEgIsVBmyr-Sk6yqEM7myfB2h6d_s6fogmT_eP45tJlI2ElJGzKk-UtZwrmUqhEgqEAWRZqnlKMq2Z4ERaDs1PmVQMMpXnFlyiBVUqBT5Al93eta8-axc2ZlmEzJUlrFxVByOVYJpT0QiTTpj5KgTvcrP2xRL8zlBiWlhmYVompmViWljmB5bZNtbz_Y06XTr7Z9zTaQRXneCrKN3u34vNbPzcFI39orPnUBmY-yKY6QsjlBMqR5JTzr8B3m-ADA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67529315</pqid></control><display><type>article</type><title>What is your diagnosis? Vertebral mass in a dog</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Khachatryan, Artashes R ; Wills, Tamara B ; Potter, Kathleen A</creator><creatorcontrib>Khachatryan, Artashes R ; Wills, Tamara B ; Potter, Kathleen A</creatorcontrib><description>: A 1‐year‐old, castrated male, mixed‐breed dog was presented for sporadic episodes of kyphosis, tremors, and vocalizing. On neurologic examination, the lesion was localized to spinal cord segments T3–L3. Magnetic resonance imaging of the spine showed an expansile mass occupying most of the ventral aspect of the spinous process of T6. Fine‐needle aspirates of the mass were examined cytologically. A moderately cellular population of pleomorphic spindle cells and abundant mucinous matrix were observed. The cytologic diagnosis was spindle cell neoplasia, with myxosarcoma and fibrosarcoma as the primary differential diagnoses. The dog was euthanized. Histopathologic evaluation of the mass and surrounding tissue confirmed a low‐grade spindle cell sarcoma, with severe compressive myelopathy and mild neutrophilic inflammation. The neoplastic cells stained positive for mucopolysaccharides with Alcian blue, resulting in a final diagnosis of low‐grade (grade 1) myxosarcoma. Fine‐needle aspiration was useful in making a preliminary diagnosis of myxosarcoma in this case. Myxosarcoma should be included in the differential diagnosis for a vertebral mass in a young dog.</description><identifier>ISSN: 0275-6382</identifier><identifier>EISSN: 1939-165X</identifier><identifier>DOI: 10.1111/j.1939-165X.2009.00116.x</identifier><identifier>PMID: 19490569</identifier><language>eng</language><publisher>Malden, USA: Blackwell Publishing Inc</publisher><subject>animal pathology ; Animals ; case studies ; cell biology ; central nervous system diseases ; complications ; Cytology ; differential staining ; disease diagnosis ; dog diseases ; Dog Diseases - diagnosis ; Dog Diseases - pathology ; Dogs ; fine-needle aspiration ; fine‐needle aspirate ; histopathology ; image analysis ; magnetic resonance imaging ; Male ; metastasis ; mucopolysaccharide ; musculoskeletal diseases ; myxosarcoma ; Myxosarcoma - diagnosis ; Myxosarcoma - pathology ; Myxosarcoma - veterinary ; neuropathy ; sarcoma ; signs and symptoms (animals and humans) ; spinal cord ; Spinal Cord Neoplasms - diagnosis ; Spinal Cord Neoplasms - pathology ; Spinal Cord Neoplasms - veterinary ; spine</subject><ispartof>Veterinary clinical pathology, 2009-06, Vol.38 (2), p.257-260</ispartof><rights>2009 American Society for Veterinary Clinical Pathology</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4566-ed7f87dd3376b65781a02aaccb93b0c9925306d3a003c672ac7ffdae895177ba3</citedby><cites>FETCH-LOGICAL-c4566-ed7f87dd3376b65781a02aaccb93b0c9925306d3a003c672ac7ffdae895177ba3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1939-165X.2009.00116.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1939-165X.2009.00116.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27922,27923,45572,45573</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19490569$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Khachatryan, Artashes R</creatorcontrib><creatorcontrib>Wills, Tamara B</creatorcontrib><creatorcontrib>Potter, Kathleen A</creatorcontrib><title>What is your diagnosis? Vertebral mass in a dog</title><title>Veterinary clinical pathology</title><addtitle>Vet Clin Pathol</addtitle><description>: A 1‐year‐old, castrated male, mixed‐breed dog was presented for sporadic episodes of kyphosis, tremors, and vocalizing. On neurologic examination, the lesion was localized to spinal cord segments T3–L3. Magnetic resonance imaging of the spine showed an expansile mass occupying most of the ventral aspect of the spinous process of T6. Fine‐needle aspirates of the mass were examined cytologically. A moderately cellular population of pleomorphic spindle cells and abundant mucinous matrix were observed. The cytologic diagnosis was spindle cell neoplasia, with myxosarcoma and fibrosarcoma as the primary differential diagnoses. The dog was euthanized. Histopathologic evaluation of the mass and surrounding tissue confirmed a low‐grade spindle cell sarcoma, with severe compressive myelopathy and mild neutrophilic inflammation. The neoplastic cells stained positive for mucopolysaccharides with Alcian blue, resulting in a final diagnosis of low‐grade (grade 1) myxosarcoma. Fine‐needle aspiration was useful in making a preliminary diagnosis of myxosarcoma in this case. Myxosarcoma should be included in the differential diagnosis for a vertebral mass in a young dog.</description><subject>animal pathology</subject><subject>Animals</subject><subject>case studies</subject><subject>cell biology</subject><subject>central nervous system diseases</subject><subject>complications</subject><subject>Cytology</subject><subject>differential staining</subject><subject>disease diagnosis</subject><subject>dog diseases</subject><subject>Dog Diseases - diagnosis</subject><subject>Dog Diseases - pathology</subject><subject>Dogs</subject><subject>fine-needle aspiration</subject><subject>fine‐needle aspirate</subject><subject>histopathology</subject><subject>image analysis</subject><subject>magnetic resonance imaging</subject><subject>Male</subject><subject>metastasis</subject><subject>mucopolysaccharide</subject><subject>musculoskeletal diseases</subject><subject>myxosarcoma</subject><subject>Myxosarcoma - diagnosis</subject><subject>Myxosarcoma - pathology</subject><subject>Myxosarcoma - veterinary</subject><subject>neuropathy</subject><subject>sarcoma</subject><subject>signs and symptoms (animals and humans)</subject><subject>spinal cord</subject><subject>Spinal Cord Neoplasms - diagnosis</subject><subject>Spinal Cord Neoplasms - pathology</subject><subject>Spinal Cord Neoplasms - veterinary</subject><subject>spine</subject><issn>0275-6382</issn><issn>1939-165X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1Lw0AQhhdRbK3-Bd2Tt6T70d3NgiBS_IKCgrZ6WybZTU1Jm7rbYPvvTUzRq3OZYeZ9Z4YHIUxJTJsYLmKquY6oFO8xI0THhFAq4-0B6v8ODlGfMCUiyRPWQychLAjhomkdox7VI02E1H00fPuADS4C3lW1x7aA-aoKRbjGM-c3LvVQ4iWEgIsVBmyr-Sk6yqEM7myfB2h6d_s6fogmT_eP45tJlI2ElJGzKk-UtZwrmUqhEgqEAWRZqnlKMq2Z4ERaDs1PmVQMMpXnFlyiBVUqBT5Al93eta8-axc2ZlmEzJUlrFxVByOVYJpT0QiTTpj5KgTvcrP2xRL8zlBiWlhmYVompmViWljmB5bZNtbz_Y06XTr7Z9zTaQRXneCrKN3u34vNbPzcFI39orPnUBmY-yKY6QsjlBMqR5JTzr8B3m-ADA</recordid><startdate>200906</startdate><enddate>200906</enddate><creator>Khachatryan, Artashes R</creator><creator>Wills, Tamara B</creator><creator>Potter, Kathleen A</creator><general>Blackwell Publishing Inc</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200906</creationdate><title>What is your diagnosis? Vertebral mass in a dog</title><author>Khachatryan, Artashes R ; Wills, Tamara B ; Potter, Kathleen A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4566-ed7f87dd3376b65781a02aaccb93b0c9925306d3a003c672ac7ffdae895177ba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>animal pathology</topic><topic>Animals</topic><topic>case studies</topic><topic>cell biology</topic><topic>central nervous system diseases</topic><topic>complications</topic><topic>Cytology</topic><topic>differential staining</topic><topic>disease diagnosis</topic><topic>dog diseases</topic><topic>Dog Diseases - diagnosis</topic><topic>Dog Diseases - pathology</topic><topic>Dogs</topic><topic>fine-needle aspiration</topic><topic>fine‐needle aspirate</topic><topic>histopathology</topic><topic>image analysis</topic><topic>magnetic resonance imaging</topic><topic>Male</topic><topic>metastasis</topic><topic>mucopolysaccharide</topic><topic>musculoskeletal diseases</topic><topic>myxosarcoma</topic><topic>Myxosarcoma - diagnosis</topic><topic>Myxosarcoma - pathology</topic><topic>Myxosarcoma - veterinary</topic><topic>neuropathy</topic><topic>sarcoma</topic><topic>signs and symptoms (animals and humans)</topic><topic>spinal cord</topic><topic>Spinal Cord Neoplasms - diagnosis</topic><topic>Spinal Cord Neoplasms - pathology</topic><topic>Spinal Cord Neoplasms - veterinary</topic><topic>spine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Khachatryan, Artashes R</creatorcontrib><creatorcontrib>Wills, Tamara B</creatorcontrib><creatorcontrib>Potter, Kathleen A</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary clinical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Khachatryan, Artashes R</au><au>Wills, Tamara B</au><au>Potter, Kathleen A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>What is your diagnosis? Vertebral mass in a dog</atitle><jtitle>Veterinary clinical pathology</jtitle><addtitle>Vet Clin Pathol</addtitle><date>2009-06</date><risdate>2009</risdate><volume>38</volume><issue>2</issue><spage>257</spage><epage>260</epage><pages>257-260</pages><issn>0275-6382</issn><eissn>1939-165X</eissn><abstract>: A 1‐year‐old, castrated male, mixed‐breed dog was presented for sporadic episodes of kyphosis, tremors, and vocalizing. On neurologic examination, the lesion was localized to spinal cord segments T3–L3. Magnetic resonance imaging of the spine showed an expansile mass occupying most of the ventral aspect of the spinous process of T6. Fine‐needle aspirates of the mass were examined cytologically. A moderately cellular population of pleomorphic spindle cells and abundant mucinous matrix were observed. The cytologic diagnosis was spindle cell neoplasia, with myxosarcoma and fibrosarcoma as the primary differential diagnoses. The dog was euthanized. Histopathologic evaluation of the mass and surrounding tissue confirmed a low‐grade spindle cell sarcoma, with severe compressive myelopathy and mild neutrophilic inflammation. The neoplastic cells stained positive for mucopolysaccharides with Alcian blue, resulting in a final diagnosis of low‐grade (grade 1) myxosarcoma. Fine‐needle aspiration was useful in making a preliminary diagnosis of myxosarcoma in this case. Myxosarcoma should be included in the differential diagnosis for a vertebral mass in a young dog.</abstract><cop>Malden, USA</cop><pub>Blackwell Publishing Inc</pub><pmid>19490569</pmid><doi>10.1111/j.1939-165X.2009.00116.x</doi><tpages>4</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0275-6382 |
ispartof | Veterinary clinical pathology, 2009-06, Vol.38 (2), p.257-260 |
issn | 0275-6382 1939-165X |
language | eng |
recordid | cdi_proquest_miscellaneous_67529315 |
source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
subjects | animal pathology Animals case studies cell biology central nervous system diseases complications Cytology differential staining disease diagnosis dog diseases Dog Diseases - diagnosis Dog Diseases - pathology Dogs fine-needle aspiration fine‐needle aspirate histopathology image analysis magnetic resonance imaging Male metastasis mucopolysaccharide musculoskeletal diseases myxosarcoma Myxosarcoma - diagnosis Myxosarcoma - pathology Myxosarcoma - veterinary neuropathy sarcoma signs and symptoms (animals and humans) spinal cord Spinal Cord Neoplasms - diagnosis Spinal Cord Neoplasms - pathology Spinal Cord Neoplasms - veterinary spine |
title | What is your diagnosis? Vertebral mass in a dog |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T00%3A40%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=What%20is%20your%20diagnosis?%20Vertebral%20mass%20in%20a%20dog&rft.jtitle=Veterinary%20clinical%20pathology&rft.au=Khachatryan,%20Artashes%20R&rft.date=2009-06&rft.volume=38&rft.issue=2&rft.spage=257&rft.epage=260&rft.pages=257-260&rft.issn=0275-6382&rft.eissn=1939-165X&rft_id=info:doi/10.1111/j.1939-165X.2009.00116.x&rft_dat=%3Cproquest_cross%3E67529315%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=67529315&rft_id=info:pmid/19490569&rfr_iscdi=true |