The overexpression of an intracellular ABCA-like transporter alters phospholipid trafficking in Leishmania

In parasites, ATP-binding cassette (ABC) transporters represent an important family of proteins related to drug resistance and other biological activities. Here we report the characterization of LtrABCA2, a new ABC transporter of the ABCA subfamily in the protozoan parasite Leishmania tropica, local...

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Veröffentlicht in:	Biochemical and biophysical research communications 2005-04, Vol.330 (1), p.349-355
Hauptverfasser:	Araújo-Santos, José María, Parodi-Talice, Adriana, Castanys, Santiago, Gamarro, Francisco
Format:	Artikel
Sprache:	eng
Schlagworte:	ABC transporter ABCA subfamily Amino Acid Sequence Animals ATP-Binding Cassette Transporters - chemistry ATP-Binding Cassette Transporters - metabolism Base Sequence DNA Primers Exocytic activity Exocytosis Fluorescent Antibody Technique, Indirect Infectivity Leishmania Leishmania tropica Leishmania tropica - metabolism Leishmania tropica - pathogenicity Molecular Sequence Data Parasites Phospholipid trafficking Phospholipids - metabolism
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