Expression and regulation of adrenomedullin in renal glomerular podocytes

Adrenomedullin (AM) is postulated to exert organ-protective effects. It is expressed in the renal glomeruli, but its roles in the glomerular podocytes have been poorly elucidated. In the present study, we investigated the expression and regulation of AM in recently established conditionally immortal...

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Veröffentlicht in:	Biochemical and biophysical research communications 2005-04, Vol.330 (1), p.178-185
Hauptverfasser:	Hino, Masayo, Nagase, Miki, Kaname, Shinya, Shibata, Shigeru, Nagase, Takashi, Oba, Shigeyoshi, Funaki, Masako, Kobayashi, Naoto, Kawachi, Hiroshi, Mundel, Peter, Fujita, Toshiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenomedullin Animals Base Sequence Cell Line Cultured murine podocyte cells DNA Primers Gene Expression Regulation - drug effects Glomerular epithelial cells Hypoxia Kidney Glomerulus - cytology Kidney Glomerulus - metabolism Mice Mitochondrial antioxidants Nephrosis rats Oxidative stress Peptides - genetics Podocyte injury Puromycin aminonucleoside Puromycin Aminonucleoside - pharmacology RNA, Messenger - genetics TNF-α Tumor Necrosis Factor-alpha - pharmacology
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