Differential modulation of the glutamate transporters GLT1, GLAST and EAAC1 by docosahexaenoic acid

At present, the ability of polyunsaturated fatty acids (PUFAs) to regulate individual glutamate transporter subtypes is poorly understood and very little information exists on the mechanism(s) by which PUFAs achieve their effects on the transport process. Here we investigate the effect of cis-4,7,10...

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Veröffentlicht in:	Brain research 2005-03, Vol.1037 (1), p.123-133
Hauptverfasser:	Berry, Colm B., Hayes, Derek, Murphy, Andrew, Wießner, Michael, Rauen, Thomas, McBean, Gethin J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Transport System X-AG - metabolism Aspartic Acid - metabolism Biological and medical sciences Calcium Calcium - physiology Calcium-Calmodulin-Dependent Protein Kinase Type 2 Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors Cell Line Cell physiology Chelating Agents - pharmacology Cloning, Molecular Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors DNA, Complementary - biosynthesis DNA, Complementary - genetics Docosahexaenoic acid Docosahexaenoic Acids - pharmacology Egtazic Acid - analogs & derivatives Egtazic Acid - pharmacology Excitatory Amino Acid Transporter 1 Excitatory Amino Acid Transporter 2 - metabolism Excitatory Amino Acid Transporter 3 Extracellular Space - enzymology Extracellular Space - metabolism Fundamental and applied biological sciences. Psychology Glutamate Glutamate Plasma Membrane Transport Proteins Humans Kinase Miscellaneous Molecular and cellular biology Plasmids - genetics Protein Kinase C - antagonists & inhibitors Symporters - metabolism Transfection Transport
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