Pyrazolyl Derivatives as Bifunctional Chelators for Labeling Tumor-Seeking Peptides with the fac-[M(CO)3]+ Moiety (M = 99mTc, Re): Synthesis, Characterization, and Biological Behavior
Radiolabeling of biologically active molecules with the [99mTc(CO)3]+ unit has been of primary interest in recent years. With this in mind, we herein report symmetric ( L 1 ) and asymmetric ( L 2 − L 5 ) pyrazolyl-containing chelators that have been evaluated in radiochemical reactions with the synt...
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Veröffentlicht in: | Bioconjugate chemistry 2005-03, Vol.16 (2), p.438-449 |
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Sprache: | eng |
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