Effects of TGF-βs on the growth, collagen synthesis and collagen lattice contraction of human dental pulp fibroblasts in vitro

Transforming growth factor-β (TGF-β) is important in regulating the repair and regeneration of damaged dental pulp. For further elucidating the roles of different isoforms of TGF-β in the healing and inflammatory processes of human dental pulp, we found that TGF-β1, TGF-β2 and TGF-β3 inhibited the g...

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Veröffentlicht in:	Archives of oral biology 2005-05, Vol.50 (5), p.469-479
Hauptverfasser:	Chan, C.P., Lan, W.H., Chang, M.C., Chen, Y.J., Lan, W.C., Chang, H.H., Jeng, J.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Division - drug effects Cell growth Cell Size - drug effects Cells, Cultured Collagen - biosynthesis Collagen lattice contraction Collagen synthesis Dental Pulp - cytology Dental Pulp - drug effects Dental Pulp - metabolism Dentistry Dose-Response Relationship, Drug Fibroblasts - drug effects Fibroblasts - metabolism Humans Protein Isoforms - pharmacology Pulp cells Recombinant Proteins - pharmacology Transforming growth factor Transforming Growth Factor beta - pharmacology Transforming Growth Factor beta1 Transforming Growth Factor beta2 Transforming Growth Factor beta3
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