Multiple myeloma

Summary Multiple myeloma is characterised by clonal proliferation of malignant plasma cells, and mounting evidence indicates that the bone marrow microenvironment of tumour cells has a pivotal role in myeloma pathogenesis. This knowledge has already expanded treatment options for patients with multi...

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Veröffentlicht in:	The Lancet (British edition) 2009-07, Vol.374 (9686), p.324-339
Hauptverfasser:	Raab, Marc S, MD, Podar, Klaus, MD, Breitkreutz, Iris, MD, Richardson, Paul G, MD, Anderson, Kenneth C, Prof
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use Biological and medical sciences Bone marrow Boronic Acids - therapeutic use Bortezomib Clinical Trials as Topic Combined Modality Therapy General aspects Genetic Predisposition to Disease - genetics Hematologic and hematopoietic diseases Humans Immunodeficiencies. Immunoglobulinopathies Immunoglobulinopathies Immunopathology Internal Medicine Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Medical sciences Melphalan - therapeutic use Multiple myeloma Multiple Myeloma - diagnosis Multiple Myeloma - drug therapy Multiple Myeloma - epidemiology Multiple Myeloma - etiology Neoplasm Staging Protease Inhibitors - therapeutic use Proteins Pyrazines - therapeutic use Remission Induction Stem Cell Transplantation Stem cells Survival Rate Thalidomide - analogs & derivatives Thalidomide - therapeutic use Transplants & implants Treatment Outcome Womens health
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