Tumour angiogenesis: Its mechanism and therapeutic implications in malignant gliomas

Abstract Angiogenesis is a key event in the progression of malignant gliomas. The presence of microvascular proliferation leads to the histological diagnosis of glioblastoma multiforme. Tumour angiogenesis involves multiple cellular processes including endothelial cell proliferation, migration, reor...

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Veröffentlicht in:	Journal of clinical neuroscience 2009-09, Vol.16 (9), p.1119-1130
Hauptverfasser:	Wong, Michael L.H, Prawira, Amy, Kaye, Andrew H, Hovens, Christopher M
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Angiogenesis Inhibitors - pharmacology Angiogenesis Inhibitors - therapeutic use Animals Brain Neoplasms - drug therapy Brain Neoplasms - pathology Clinical trials Glioma Glioma - blood supply Glioma - drug therapy Glioma - pathology Humans Neoplasms - blood supply Neoplasms - drug therapy Neoplasms - pathology Neovascularization, Pathologic - drug therapy Neovascularization, Pathologic - pathology Neovascularization, Pathologic - physiopathology Neurology Regional Blood Flow - drug effects
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