Macrophage receptors and immune recognition
Macrophages express a broad range of plasma membrane receptors that mediate their interactions with natural and altered-self components of the host as well as a range of microorganisms. Recognition is followed by surface changes, uptake, signaling, and altered gene expression, contributing to homeos...
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| Veröffentlicht in: | Annual review of immunology 2005-01, Vol.23 (1), p.901-944 |
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| container_end_page | 944 |
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| container_issue | 1 |
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| container_title | Annual review of immunology |
| container_volume | 23 |
| creator | Taylor, P R Martinez-Pomares, L Stacey, M Lin, H-H Brown, G D Gordon, S |
| description | Macrophages express a broad range of plasma membrane receptors that mediate their interactions with natural and altered-self components of the host as well as a range of microorganisms. Recognition is followed by surface changes, uptake, signaling, and altered gene expression, contributing to homeostasis, host defense, innate effector mechanisms, and the induction of acquired immunity. This review covers recent studies of selected families of structurally defined molecules, studies that have improved understanding of ligand discrimination in the absence of opsonins and differential responses by macrophages and related myeloid cells. |
| doi_str_mv | 10.1146/annurev.immunol.23.021704.115816 |
| format | Article |
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| ispartof | Annual review of immunology, 2005-01, Vol.23 (1), p.901-944 |
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| language | eng |
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| source | Annual Reviews Complete A-Z List; MEDLINE |
| subjects | Animals Apoptosis Humans Immunity, Innate Macrophage Activation Macrophages - immunology Macrophages - microbiology Mice Models, Immunological Receptors, Cell Surface - chemistry Receptors, Cell Surface - immunology Receptors, Immunologic - chemistry Receptors, Immunologic - metabolism Spleen - cytology Spleen - immunology |
| title | Macrophage receptors and immune recognition |
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