Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women

Summary Background The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine was immunogenic, generally well tolerated, and effective against HPV-16 or HPV-18 infections, and associated precancerous lesions in an event-triggered interim analysis of the phase III randomised, double-blind, controll...

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Veröffentlicht in:	The Lancet (British edition) 2009-07, Vol.374 (9686), p.301-314
Hauptverfasser:	Paavonen, J, Prof, Naud, P, Prof, Salmerón, J, Prof, Wheeler, CM, Prof, Chow, S-N, Prof, Apter, D, MD, Kitchener, H, Prof, Castellsague, X, MD, Teixeira, JC, MD, Skinner, SR, PhD, Hedrick, J, MD, Jaisamrarn, U, MD, Limson, G, Prof, Garland, S, Prof, Szarewski, A, PhD, Romanowski, B, Prof, Aoki, FY, Prof, Schwarz, TF, Prof, Poppe, WAJ, Prof, Bosch, FX, MD, Jenkins, D, Prof, Hardt, K, PhD, Zahaf, T, PhD, Descamps, D, MD, Struyf, F, MD, Lehtinen, M, Prof, Dubin, G, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult ATP Autoimmune diseases Biomedical research Cervical cancer Cervical Intraepithelial Neoplasia - prevention & control Cervical Intraepithelial Neoplasia - virology Deoxyribonucleic acid DNA Double-Blind Method Female Human papillomavirus Human papillomavirus 16 Human papillomavirus 18 Humans Immunization Internal Medicine Lesions Mass Vaccination Neoplasm Staging Papillomavirus Infections - complications Papillomavirus Infections - virology Papillomavirus Vaccines - immunology Precancerous Conditions - prevention & control Precancerous Conditions - virology Public health Safety Sexual Behavior Treatment Outcome Uterine Cervical Neoplasms - prevention & control Uterine Cervical Neoplasms - virology Vaccines Vaginal Smears Womens health Young Adult Young adults
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