Leukemia fusion proteins and co-repressor complexes: Changing paradigms

Many cases of acute myelogenous leukemia (AML) are characterized by non‐random chromosomal translocations that fuse a DNA‐binding protein with a transcriptional regulator, which in turn may aberrantly recruit a co‐repressor complex. The similarities in this pattern between different AML chimeric fus...

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Veröffentlicht in:	Journal of cellular biochemistry 2005-04, Vol.94 (5), p.864-869
Hauptverfasser:	Redner, Robert L., Liu, Johnson M.
Format:	Artikel
Sprache:	eng
Schlagworte:	acute myeloid leukemia AML-ETO co-repressors HDAC Histone Deacetylase Inhibitors Humans Leukemia - metabolism N-COR PML-RAR Recombinant Fusion Proteins - metabolism Repressor Proteins - metabolism SMRT
Online-Zugang:	Volltext
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