HCV core protein localizes in the nuclei of nonparenchymal liver cells from chronically HCV-infected patients

Understanding the mechanism of hepatitis C virus (HCV) pathogenesis is an important part of HCV research. Recent experimental evidence suggests that the HCV core protein (HCcAg) has numerous functional activities. These properties suggest that HCcAg, in concert with cellular factors, may contribute...

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Veröffentlicht in:	Biochemical and biophysical research communications 2005-04, Vol.329 (4), p.1320-1328
Hauptverfasser:	Falcón, Viviana, Acosta-Rivero, Nelson, Shibayama, Mineko, Chinea, Glay, Gavilondo, Jorge V., de la Rosa, María C., Menéndez, Ivón, Gra, Bienvenido, Dueñas-Carrera, Santiago, Viña, Ariel, García, Waldo, González-Bravo, Maritza, Luna-Munoz, Jose, Miranda-Sanchez, Magdalena, Morales-Grillo, Juan, Kouri, Juan, Tsutsumi, Victor
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biopsy Cell Nucleus - metabolism Cell Nucleus - ultrastructure Core protein Female Hepacivirus - metabolism Hepatitis C virus Hepatitis C, Chronic - metabolism Hepatitis C, Chronic - pathology Hepatocytes - metabolism Hepatocytes - pathology Hepatocytes - ultrastructure Humans Immunoelectron microscopy Male Microscopy, Electron, Transmission Middle Aged Viral Core Proteins - metabolism
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