Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering

Polycaprolactone (PCL) is a bioresorbable polymer with potential applications for bone and cartilage repair. In this work, porous PCL scaffolds were computationally designed and then fabricated via selective laser sintering (SLS), a rapid prototyping technique. The microstructure and mechanical prop...

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Veröffentlicht in:	Biomaterials 2005-08, Vol.26 (23), p.4817-4827
Hauptverfasser:	Williams, Jessica M., Adewunmi, Adebisi, Schek, Rachel M., Flanagan, Colleen L., Krebsbach, Paul H., Feinberg, Stephen E., Hollister, Scott J., Das, Suman
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioprosthesis Bone Substitutes - chemistry Bone tissue engineering Cell Culture Techniques - methods Cell Differentiation - physiology Cell Proliferation Cell Survival Cells, Cultured Computer Simulation Computer-Aided Design Elasticity Feasibility Studies Fibroblasts - cytology Fibroblasts - physiology Finite element analysis Guided Tissue Regeneration - instrumentation Guided Tissue Regeneration - methods Hot Temperature Humans Laser manufacturing Lasers Mandibular Condyle - cytology Mandibular Condyle - physiology Mechanical properties Micro-computed tomography (μCT) Models, Biological Osteoblasts - cytology Osteoblasts - physiology Polycaprolactone Polyesters - analysis Polyesters - chemistry Porosity Prosthesis Design - methods Rapid prototyping Solid free-form fabrication Swine Swine, Miniature Tissue Engineering - methods
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