Developments in the rat adjuvant arthritis model and its use in therapeutic evaluation of novel non-invasive treatment by SOD in Transfersomes

The aim of this study was firstly to refine a rat model of arthritis, the adjuvant arthritis (AA) model, by studying the time course of the disease, introducing new evaluation methods such as haematological and biochemical parameters in order to identify the main stages of the disease. An optimisati...

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Veröffentlicht in:Journal of controlled release 2005-03, Vol.103 (2), p.419-434
Hauptverfasser: Simões, S.I., Delgado, T.C., Lopes, R.M., Jesus, S., Ferreira, A.A., Morais, J.A., Cruz, M.E.M., Corvo, M.L., Martins, M.B.F.
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Sprache:eng
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