Factors Predicting Successful Labor Induction With Dinoprostone and Misoprostol Vaginal Inserts

To evaluate the maternal and pregnancy characteristics that independently predict successful induction of labor, defined as vaginal delivery. The study was a secondary analysis of the data collected during the Misoprostol Vaginal Insert Trial, a multisite, double-blind, randomized trial of women req...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Obstetrics and gynecology (New York. 1953) 2009-08, Vol.114 (2), p.261-267
Hauptverfasser: Pevzner, Leo, Rayburn, William F., Rumney, Pamela, Wing, Deborah A.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 267
container_issue 2
container_start_page 261
container_title Obstetrics and gynecology (New York. 1953)
container_volume 114
creator Pevzner, Leo
Rayburn, William F.
Rumney, Pamela
Wing, Deborah A.
description To evaluate the maternal and pregnancy characteristics that independently predict successful induction of labor, defined as vaginal delivery. The study was a secondary analysis of the data collected during the Misoprostol Vaginal Insert Trial, a multisite, double-blind, randomized trial of women requiring cervical ripening before induction of labor. The primary outcome was to estimate the maternal and pregnancy characteristics that independently predict successful induction of labor. Univariable and multiple regression analyses were performed for maternal and pregnancy-related factors that potentially could predict a successful induction of labor. A total of 1,274 patients had sufficient labor and delivery data for a comparative analysis. Nine hundred sixteen (72%) induced patients subsequently had vaginal deliveries. Multiparity (odds ratio [OR] 4.63, 95% confidence interval [CI] 3.39-6.32, P
doi_str_mv 10.1097/AOG.0b013e3181ad9377
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67508199</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67508199</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3801-17ca506f0e5c9ed8913f28b019ffa627dacd26b42cacdbfa52e86166fb231933</originalsourceid><addsrcrecordid>eNpdkV1PFTEQhhsjkSP4D4zZG71bnGl3-3FJUJDkGEgg6l3T7bacak8X290Q_70lbCTxajrt885M3yHkLcIJghIfT68uTmAAZI6hRDMqJsQLskEpWEsZ-_GSbACoaoXsukPyupSfAIBcsVfkEBWnVEm-Ifrc2HnKpbnObgx2DumuuVmsdaX4JTZbM0y5uUzjUp-m1HwP8675FNJ0n6cyT8k1Jo3N11DWi9h8M3chmVg1xeW5HJMDb2Jxb9Z4RG7PP9-efWm3VxeXZ6fb1jIJ2KKwpgfuwfVWuVEqZJ7K-jvlveFUjMaOlA8dtfUweNNTJzly7gfKUDF2RD48la1j_F5cmfU-FOtiNMlNS9Fc9CBRqQp2T6Ct85bsvL7PYW_yH42gH33V1Vf9v69V9m6tvwx7Nz6LViMr8H4FTLEm-mySDeUfR1EooB0-93-Y4uxy-RWXB5f1zpk473TdEHDaQ0sBFMiatY9LQ_YX9lSS4g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67508199</pqid></control><display><type>article</type><title>Factors Predicting Successful Labor Induction With Dinoprostone and Misoprostol Vaginal Inserts</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Pevzner, Leo ; Rayburn, William F. ; Rumney, Pamela ; Wing, Deborah A.</creator><creatorcontrib>Pevzner, Leo ; Rayburn, William F. ; Rumney, Pamela ; Wing, Deborah A.</creatorcontrib><description>To evaluate the maternal and pregnancy characteristics that independently predict successful induction of labor, defined as vaginal delivery. The study was a secondary analysis of the data collected during the Misoprostol Vaginal Insert Trial, a multisite, double-blind, randomized trial of women requiring cervical ripening before induction of labor. The primary outcome was to estimate the maternal and pregnancy characteristics that independently predict successful induction of labor. Univariable and multiple regression analyses were performed for maternal and pregnancy-related factors that potentially could predict a successful induction of labor. A total of 1,274 patients had sufficient labor and delivery data for a comparative analysis. Nine hundred sixteen (72%) induced patients subsequently had vaginal deliveries. Multiparity (odds ratio [OR] 4.63, 95% confidence interval [CI] 3.39-6.32, P&lt;.001), maternal body mass index (BMI) less than 30 (OR 1.69, 95% CI 1.32-2.22, P&lt;.001) and height greater than 5'5" (OR 1.47, 95% CI 1.15-1.9, P=.002), baseline modified Bishop score of 4 (OR 2.15, 95% CI 1.12-4.20, P=.047), and birth weight below 4,000 g (OR 2.17, 95% CI 1.51-3.13, P&lt;.001) were significant for predicting successful induction of labor. Logistic regression analysis was performed to evaluate each factor as an independent predictor. In addition to the above-mentioned factors, maternal age younger than 35 years (OR 1.81, 95% CI 1.15-2.86, P=.01) and Hispanic race (OR 1.45, 95% CI 1.02-2.05, P=.036) each proved to significantly favor a successful induction. Conversely, African-American race was correlated with a higher incidence of cesarean delivery (OR 1.47, 95% CI 1.02-2.13, P&lt;.001). Maternal characteristics such as BMI, parity, age, and race and neonatal birth weight are important variables to consider when predicting a successful induction of labor. The nearly 30% rate of cesarean delivery in this study underscores the importance of selecting appropriate candidates. II.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>DOI: 10.1097/AOG.0b013e3181ad9377</identifier><identifier>PMID: 19622986</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>Hagerstown, MD: by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved</publisher><subject>Adult ; Biological and medical sciences ; Birth Weight ; Body Height ; Body Mass Index ; Continental Population Groups ; Delivery. Postpartum. Lactation ; Digestive system ; Dinoprostone - administration &amp; dosage ; Double-Blind Method ; Female ; Gynecology. Andrology. Obstetrics ; Humans ; Infant, Newborn ; Labor, Induced - methods ; Maternal Age ; Medical sciences ; Misoprostol - administration &amp; dosage ; Oxytocics - administration &amp; dosage ; Parity ; Pharmacology. Drug treatments ; Pregnancy ; Suppositories ; Vagina</subject><ispartof>Obstetrics and gynecology (New York. 1953), 2009-08, Vol.114 (2), p.261-267</ispartof><rights>by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.</rights><rights>2009 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3801-17ca506f0e5c9ed8913f28b019ffa627dacd26b42cacdbfa52e86166fb231933</citedby><cites>FETCH-LOGICAL-c3801-17ca506f0e5c9ed8913f28b019ffa627dacd26b42cacdbfa52e86166fb231933</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=21790241$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19622986$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pevzner, Leo</creatorcontrib><creatorcontrib>Rayburn, William F.</creatorcontrib><creatorcontrib>Rumney, Pamela</creatorcontrib><creatorcontrib>Wing, Deborah A.</creatorcontrib><title>Factors Predicting Successful Labor Induction With Dinoprostone and Misoprostol Vaginal Inserts</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>To evaluate the maternal and pregnancy characteristics that independently predict successful induction of labor, defined as vaginal delivery. The study was a secondary analysis of the data collected during the Misoprostol Vaginal Insert Trial, a multisite, double-blind, randomized trial of women requiring cervical ripening before induction of labor. The primary outcome was to estimate the maternal and pregnancy characteristics that independently predict successful induction of labor. Univariable and multiple regression analyses were performed for maternal and pregnancy-related factors that potentially could predict a successful induction of labor. A total of 1,274 patients had sufficient labor and delivery data for a comparative analysis. Nine hundred sixteen (72%) induced patients subsequently had vaginal deliveries. Multiparity (odds ratio [OR] 4.63, 95% confidence interval [CI] 3.39-6.32, P&lt;.001), maternal body mass index (BMI) less than 30 (OR 1.69, 95% CI 1.32-2.22, P&lt;.001) and height greater than 5'5" (OR 1.47, 95% CI 1.15-1.9, P=.002), baseline modified Bishop score of 4 (OR 2.15, 95% CI 1.12-4.20, P=.047), and birth weight below 4,000 g (OR 2.17, 95% CI 1.51-3.13, P&lt;.001) were significant for predicting successful induction of labor. Logistic regression analysis was performed to evaluate each factor as an independent predictor. In addition to the above-mentioned factors, maternal age younger than 35 years (OR 1.81, 95% CI 1.15-2.86, P=.01) and Hispanic race (OR 1.45, 95% CI 1.02-2.05, P=.036) each proved to significantly favor a successful induction. Conversely, African-American race was correlated with a higher incidence of cesarean delivery (OR 1.47, 95% CI 1.02-2.13, P&lt;.001). Maternal characteristics such as BMI, parity, age, and race and neonatal birth weight are important variables to consider when predicting a successful induction of labor. The nearly 30% rate of cesarean delivery in this study underscores the importance of selecting appropriate candidates. II.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Birth Weight</subject><subject>Body Height</subject><subject>Body Mass Index</subject><subject>Continental Population Groups</subject><subject>Delivery. Postpartum. Lactation</subject><subject>Digestive system</subject><subject>Dinoprostone - administration &amp; dosage</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Labor, Induced - methods</subject><subject>Maternal Age</subject><subject>Medical sciences</subject><subject>Misoprostol - administration &amp; dosage</subject><subject>Oxytocics - administration &amp; dosage</subject><subject>Parity</subject><subject>Pharmacology. Drug treatments</subject><subject>Pregnancy</subject><subject>Suppositories</subject><subject>Vagina</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkV1PFTEQhhsjkSP4D4zZG71bnGl3-3FJUJDkGEgg6l3T7bacak8X290Q_70lbCTxajrt885M3yHkLcIJghIfT68uTmAAZI6hRDMqJsQLskEpWEsZ-_GSbACoaoXsukPyupSfAIBcsVfkEBWnVEm-Ifrc2HnKpbnObgx2DumuuVmsdaX4JTZbM0y5uUzjUp-m1HwP8675FNJ0n6cyT8k1Jo3N11DWi9h8M3chmVg1xeW5HJMDb2Jxb9Z4RG7PP9-efWm3VxeXZ6fb1jIJ2KKwpgfuwfVWuVEqZJ7K-jvlveFUjMaOlA8dtfUweNNTJzly7gfKUDF2RD48la1j_F5cmfU-FOtiNMlNS9Fc9CBRqQp2T6Ct85bsvL7PYW_yH42gH33V1Vf9v69V9m6tvwx7Nz6LViMr8H4FTLEm-mySDeUfR1EooB0-93-Y4uxy-RWXB5f1zpk473TdEHDaQ0sBFMiatY9LQ_YX9lSS4g</recordid><startdate>20090801</startdate><enddate>20090801</enddate><creator>Pevzner, Leo</creator><creator>Rayburn, William F.</creator><creator>Rumney, Pamela</creator><creator>Wing, Deborah A.</creator><general>by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved</general><general>Lippincott Williams &amp; Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20090801</creationdate><title>Factors Predicting Successful Labor Induction With Dinoprostone and Misoprostol Vaginal Inserts</title><author>Pevzner, Leo ; Rayburn, William F. ; Rumney, Pamela ; Wing, Deborah A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3801-17ca506f0e5c9ed8913f28b019ffa627dacd26b42cacdbfa52e86166fb231933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Birth Weight</topic><topic>Body Height</topic><topic>Body Mass Index</topic><topic>Continental Population Groups</topic><topic>Delivery. Postpartum. Lactation</topic><topic>Digestive system</topic><topic>Dinoprostone - administration &amp; dosage</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Labor, Induced - methods</topic><topic>Maternal Age</topic><topic>Medical sciences</topic><topic>Misoprostol - administration &amp; dosage</topic><topic>Oxytocics - administration &amp; dosage</topic><topic>Parity</topic><topic>Pharmacology. Drug treatments</topic><topic>Pregnancy</topic><topic>Suppositories</topic><topic>Vagina</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pevzner, Leo</creatorcontrib><creatorcontrib>Rayburn, William F.</creatorcontrib><creatorcontrib>Rumney, Pamela</creatorcontrib><creatorcontrib>Wing, Deborah A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pevzner, Leo</au><au>Rayburn, William F.</au><au>Rumney, Pamela</au><au>Wing, Deborah A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors Predicting Successful Labor Induction With Dinoprostone and Misoprostol Vaginal Inserts</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>2009-08-01</date><risdate>2009</risdate><volume>114</volume><issue>2</issue><spage>261</spage><epage>267</epage><pages>261-267</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>To evaluate the maternal and pregnancy characteristics that independently predict successful induction of labor, defined as vaginal delivery. The study was a secondary analysis of the data collected during the Misoprostol Vaginal Insert Trial, a multisite, double-blind, randomized trial of women requiring cervical ripening before induction of labor. The primary outcome was to estimate the maternal and pregnancy characteristics that independently predict successful induction of labor. Univariable and multiple regression analyses were performed for maternal and pregnancy-related factors that potentially could predict a successful induction of labor. A total of 1,274 patients had sufficient labor and delivery data for a comparative analysis. Nine hundred sixteen (72%) induced patients subsequently had vaginal deliveries. Multiparity (odds ratio [OR] 4.63, 95% confidence interval [CI] 3.39-6.32, P&lt;.001), maternal body mass index (BMI) less than 30 (OR 1.69, 95% CI 1.32-2.22, P&lt;.001) and height greater than 5'5" (OR 1.47, 95% CI 1.15-1.9, P=.002), baseline modified Bishop score of 4 (OR 2.15, 95% CI 1.12-4.20, P=.047), and birth weight below 4,000 g (OR 2.17, 95% CI 1.51-3.13, P&lt;.001) were significant for predicting successful induction of labor. Logistic regression analysis was performed to evaluate each factor as an independent predictor. In addition to the above-mentioned factors, maternal age younger than 35 years (OR 1.81, 95% CI 1.15-2.86, P=.01) and Hispanic race (OR 1.45, 95% CI 1.02-2.05, P=.036) each proved to significantly favor a successful induction. Conversely, African-American race was correlated with a higher incidence of cesarean delivery (OR 1.47, 95% CI 1.02-2.13, P&lt;.001). Maternal characteristics such as BMI, parity, age, and race and neonatal birth weight are important variables to consider when predicting a successful induction of labor. The nearly 30% rate of cesarean delivery in this study underscores the importance of selecting appropriate candidates. II.</abstract><cop>Hagerstown, MD</cop><pub>by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved</pub><pmid>19622986</pmid><doi>10.1097/AOG.0b013e3181ad9377</doi><tpages>7</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0029-7844
ispartof Obstetrics and gynecology (New York. 1953), 2009-08, Vol.114 (2), p.261-267
issn 0029-7844
1873-233X
language eng
recordid cdi_proquest_miscellaneous_67508199
source MEDLINE; Journals@Ovid Complete
subjects Adult
Biological and medical sciences
Birth Weight
Body Height
Body Mass Index
Continental Population Groups
Delivery. Postpartum. Lactation
Digestive system
Dinoprostone - administration & dosage
Double-Blind Method
Female
Gynecology. Andrology. Obstetrics
Humans
Infant, Newborn
Labor, Induced - methods
Maternal Age
Medical sciences
Misoprostol - administration & dosage
Oxytocics - administration & dosage
Parity
Pharmacology. Drug treatments
Pregnancy
Suppositories
Vagina
title Factors Predicting Successful Labor Induction With Dinoprostone and Misoprostol Vaginal Inserts
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T23%3A41%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Factors%20Predicting%20Successful%20Labor%20Induction%20With%20Dinoprostone%20and%20Misoprostol%20Vaginal%20Inserts&rft.jtitle=Obstetrics%20and%20gynecology%20(New%20York.%201953)&rft.au=Pevzner,%20Leo&rft.date=2009-08-01&rft.volume=114&rft.issue=2&rft.spage=261&rft.epage=267&rft.pages=261-267&rft.issn=0029-7844&rft.eissn=1873-233X&rft.coden=OBGNAS&rft_id=info:doi/10.1097/AOG.0b013e3181ad9377&rft_dat=%3Cproquest_cross%3E67508199%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=67508199&rft_id=info:pmid/19622986&rfr_iscdi=true