Olanzapine for the treatment of hemiballismus: A case report
Mukand JA, Fitzsimmons C, Wennemer HK, Carrillo A, Cai C, Bailey KM. Olanzapine for the treatment of hemiballismus: a case report. Hemiballismus is a rare movement disorder characterized by involuntary, large amplitude movements of the limbs of 1 side of the body. We describe the case of a man in hi...
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| Veröffentlicht in: | Archives of physical medicine and rehabilitation 2005-03, Vol.86 (3), p.587-590 |
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| creator | Mukand, Jon A. Fitzsimmons, Colleen Wennemer, Heidi K. Carrillo, Adriana Cai, Chunbo Bailey, Kim M. |
| description | Mukand JA, Fitzsimmons C, Wennemer HK, Carrillo A, Cai C, Bailey KM. Olanzapine for the treatment of hemiballismus: a case report.
Hemiballismus is a rare movement disorder characterized by involuntary, large amplitude movements of the limbs of 1 side of the body. We describe the case of a man in his late sixties with slurred speech, agitation, and right-sided hemiballismus resulting from a left thalamic hemorrhagic stroke. Treatment with haloperidol was unsuccessful, but both the hemiballismus and agitation diminished significantly after initiation of olanzapine (Zyprexa). The improvement in the hemiballismus was quantified by recording the number of hemiballistic movements that occurred while the patient performed standardized 30-minute sessions (daily for 5d). With the first task (reaching within the base of support while seated), the average number of hemiballismic movements per session decreased from a baseline of 23.5 to 3.0 in the upper extremity and from 20.5 to 7.0 in the lower extremity. With the second task (catching a ball while seated), the abnormal movements decreased from 52 to 6.3 in the upper extremity and from 34.5 to 2.7 in the lower extremity. This case suggests that olanzapine may be a valuable pharmacologic alternative for patients with hemiballismus. |
| doi_str_mv | 10.1016/j.apmr.2004.05.012 |
| format | Article |
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Hemiballismus is a rare movement disorder characterized by involuntary, large amplitude movements of the limbs of 1 side of the body. We describe the case of a man in his late sixties with slurred speech, agitation, and right-sided hemiballismus resulting from a left thalamic hemorrhagic stroke. Treatment with haloperidol was unsuccessful, but both the hemiballismus and agitation diminished significantly after initiation of olanzapine (Zyprexa). The improvement in the hemiballismus was quantified by recording the number of hemiballistic movements that occurred while the patient performed standardized 30-minute sessions (daily for 5d). With the first task (reaching within the base of support while seated), the average number of hemiballismic movements per session decreased from a baseline of 23.5 to 3.0 in the upper extremity and from 20.5 to 7.0 in the lower extremity. With the second task (catching a ball while seated), the abnormal movements decreased from 52 to 6.3 in the upper extremity and from 34.5 to 2.7 in the lower extremity. This case suggests that olanzapine may be a valuable pharmacologic alternative for patients with hemiballismus.</description><identifier>ISSN: 0003-9993</identifier><identifier>EISSN: 1532-821X</identifier><identifier>DOI: 10.1016/j.apmr.2004.05.012</identifier><identifier>PMID: 15759249</identifier><identifier>CODEN: APMHAI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Antipsychotic agents ; Antipsychotic Agents - therapeutic use ; Benzodiazepines - therapeutic use ; Biological and medical sciences ; Case report ; Dyskinesias - drug therapy ; Dyskinesias - etiology ; Dyskinesias - physiopathology ; Hemiballismus ; Humans ; Male ; Medical sciences ; Miscellaneous ; Nervous system (semeiology, syndromes) ; Nervous system as a whole ; Neurology ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Rehabilitation ; Stroke ; Stroke - complications ; Stroke Rehabilitation ; Vascular diseases and vascular malformations of the nervous system</subject><ispartof>Archives of physical medicine and rehabilitation, 2005-03, Vol.86 (3), p.587-590</ispartof><rights>2005 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation</rights><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c384t-fa13669eb95cc25ae1d109d803736808e1294c02f8aab32c79d5d2428b229bcb3</citedby><cites>FETCH-LOGICAL-c384t-fa13669eb95cc25ae1d109d803736808e1294c02f8aab32c79d5d2428b229bcb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.apmr.2004.05.012$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27907,27908,45978</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16607595$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15759249$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mukand, Jon A.</creatorcontrib><creatorcontrib>Fitzsimmons, Colleen</creatorcontrib><creatorcontrib>Wennemer, Heidi K.</creatorcontrib><creatorcontrib>Carrillo, Adriana</creatorcontrib><creatorcontrib>Cai, Chunbo</creatorcontrib><creatorcontrib>Bailey, Kim M.</creatorcontrib><title>Olanzapine for the treatment of hemiballismus: A case report</title><title>Archives of physical medicine and rehabilitation</title><addtitle>Arch Phys Med Rehabil</addtitle><description>Mukand JA, Fitzsimmons C, Wennemer HK, Carrillo A, Cai C, Bailey KM. Olanzapine for the treatment of hemiballismus: a case report.
Hemiballismus is a rare movement disorder characterized by involuntary, large amplitude movements of the limbs of 1 side of the body. We describe the case of a man in his late sixties with slurred speech, agitation, and right-sided hemiballismus resulting from a left thalamic hemorrhagic stroke. Treatment with haloperidol was unsuccessful, but both the hemiballismus and agitation diminished significantly after initiation of olanzapine (Zyprexa). The improvement in the hemiballismus was quantified by recording the number of hemiballistic movements that occurred while the patient performed standardized 30-minute sessions (daily for 5d). With the first task (reaching within the base of support while seated), the average number of hemiballismic movements per session decreased from a baseline of 23.5 to 3.0 in the upper extremity and from 20.5 to 7.0 in the lower extremity. With the second task (catching a ball while seated), the abnormal movements decreased from 52 to 6.3 in the upper extremity and from 34.5 to 2.7 in the lower extremity. This case suggests that olanzapine may be a valuable pharmacologic alternative for patients with hemiballismus.</description><subject>Aged</subject><subject>Antipsychotic agents</subject><subject>Antipsychotic Agents - therapeutic use</subject><subject>Benzodiazepines - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Case report</subject><subject>Dyskinesias - drug therapy</subject><subject>Dyskinesias - etiology</subject><subject>Dyskinesias - physiopathology</subject><subject>Hemiballismus</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Nervous system as a whole</subject><subject>Neurology</subject><subject>Radiotherapy. 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Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Rehabilitation</topic><topic>Stroke</topic><topic>Stroke - complications</topic><topic>Stroke Rehabilitation</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mukand, Jon A.</creatorcontrib><creatorcontrib>Fitzsimmons, Colleen</creatorcontrib><creatorcontrib>Wennemer, Heidi K.</creatorcontrib><creatorcontrib>Carrillo, Adriana</creatorcontrib><creatorcontrib>Cai, Chunbo</creatorcontrib><creatorcontrib>Bailey, Kim M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of physical medicine and rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mukand, Jon A.</au><au>Fitzsimmons, Colleen</au><au>Wennemer, Heidi K.</au><au>Carrillo, Adriana</au><au>Cai, Chunbo</au><au>Bailey, Kim M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Olanzapine for the treatment of hemiballismus: A case report</atitle><jtitle>Archives of physical medicine and rehabilitation</jtitle><addtitle>Arch Phys Med Rehabil</addtitle><date>2005-03-01</date><risdate>2005</risdate><volume>86</volume><issue>3</issue><spage>587</spage><epage>590</epage><pages>587-590</pages><issn>0003-9993</issn><eissn>1532-821X</eissn><coden>APMHAI</coden><abstract>Mukand JA, Fitzsimmons C, Wennemer HK, Carrillo A, Cai C, Bailey KM. Olanzapine for the treatment of hemiballismus: a case report.
Hemiballismus is a rare movement disorder characterized by involuntary, large amplitude movements of the limbs of 1 side of the body. We describe the case of a man in his late sixties with slurred speech, agitation, and right-sided hemiballismus resulting from a left thalamic hemorrhagic stroke. Treatment with haloperidol was unsuccessful, but both the hemiballismus and agitation diminished significantly after initiation of olanzapine (Zyprexa). The improvement in the hemiballismus was quantified by recording the number of hemiballistic movements that occurred while the patient performed standardized 30-minute sessions (daily for 5d). With the first task (reaching within the base of support while seated), the average number of hemiballismic movements per session decreased from a baseline of 23.5 to 3.0 in the upper extremity and from 20.5 to 7.0 in the lower extremity. With the second task (catching a ball while seated), the abnormal movements decreased from 52 to 6.3 in the upper extremity and from 34.5 to 2.7 in the lower extremity. This case suggests that olanzapine may be a valuable pharmacologic alternative for patients with hemiballismus.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>15759249</pmid><doi>10.1016/j.apmr.2004.05.012</doi><tpages>4</tpages></addata></record> |
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| subjects | Aged Antipsychotic agents Antipsychotic Agents - therapeutic use Benzodiazepines - therapeutic use Biological and medical sciences Case report Dyskinesias - drug therapy Dyskinesias - etiology Dyskinesias - physiopathology Hemiballismus Humans Male Medical sciences Miscellaneous Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Rehabilitation Stroke Stroke - complications Stroke Rehabilitation Vascular diseases and vascular malformations of the nervous system |
| title | Olanzapine for the treatment of hemiballismus: A case report |
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