Long-pulsed neodymium:yttrium-aluminum-garnet laser treatment for port-wine stains
Laser treatment of port-wine stain (PWS) might be improved using a deeply penetrating wavelength. PWSs in 17 patients were treated 3 times with a 595-nm pulsed dye laser (PDL) and a 1064-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser. Fluences of 1.0, 0.8, and 0.6 times the minimum purpura dose...
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| Veröffentlicht in: | Journal of the American Academy of Dermatology 2005-03, Vol.52 (3), p.480-490 |
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| container_title | Journal of the American Academy of Dermatology |
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| creator | Yang, Marjorie U. Yaroslavsky, Anna N. Farinelli, William A. Flotte, Thomas J. Rius-Diaz, Francisca Tsao, Sandy S. Anderson, R. Rox |
| description | Laser treatment of port-wine stain (PWS) might be improved using a deeply penetrating wavelength.
PWSs in 17 patients were treated 3 times with a 595-nm pulsed dye laser (PDL) and a 1064-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser. Fluences of 1.0, 0.8, and 0.6 times the minimum purpura dose (MPD) were used for Nd:YAG laser. Posttreatment biopsy specimens were taken. Blind assessment and quantitative analysis of PWS clearing were performed from digital photographs.
MPD for Nd:YAG laser varied widely, from 40 to 250 J/cm
2. Purpura lasted longer after PDL. Treatment achieved similar 50% to 75% clearing with both PDL and Nd:YAG laser at 1 MPD. Nd:YAG caused greater perivascular and epidermal injury. Scarring occurred in the only patient treated with a Nd:YAG fluence greater than 1 MPD. Patients preferred Nd:YAG laser because of their faster recovery.
Nd:YAG laser used at MPD is as effective as PDL for treating PWS. Nd:YAG laser fluences higher than MPD may cause scarring. |
| doi_str_mv | 10.1016/j.jaad.2004.10.876 |
| format | Article |
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PWSs in 17 patients were treated 3 times with a 595-nm pulsed dye laser (PDL) and a 1064-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser. Fluences of 1.0, 0.8, and 0.6 times the minimum purpura dose (MPD) were used for Nd:YAG laser. Posttreatment biopsy specimens were taken. Blind assessment and quantitative analysis of PWS clearing were performed from digital photographs.
MPD for Nd:YAG laser varied widely, from 40 to 250 J/cm
2. Purpura lasted longer after PDL. Treatment achieved similar 50% to 75% clearing with both PDL and Nd:YAG laser at 1 MPD. Nd:YAG caused greater perivascular and epidermal injury. Scarring occurred in the only patient treated with a Nd:YAG fluence greater than 1 MPD. Patients preferred Nd:YAG laser because of their faster recovery.
Nd:YAG laser used at MPD is as effective as PDL for treating PWS. Nd:YAG laser fluences higher than MPD may cause scarring.</description><identifier>ISSN: 0190-9622</identifier><identifier>EISSN: 1097-6787</identifier><identifier>DOI: 10.1016/j.jaad.2004.10.876</identifier><identifier>PMID: 15761427</identifier><identifier>CODEN: JAADDB</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Dermatology ; Hereditary diseases of the skin. Congenital diseases of the skin. Haemangioma of the skin, of mucosae and of soft tissue ; Humans ; Laser Therapy ; Medical sciences ; Middle Aged ; Pilot Projects ; Port-Wine Stain - pathology ; Port-Wine Stain - radiotherapy</subject><ispartof>Journal of the American Academy of Dermatology, 2005-03, Vol.52 (3), p.480-490</ispartof><rights>2005 American Academy of Dermatology, Inc.</rights><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c384t-cb305058e1865a30a5e7e1cb020d3ae4d0ba1682ad4cc2b0168c4c47b2e294e73</citedby><cites>FETCH-LOGICAL-c384t-cb305058e1865a30a5e7e1cb020d3ae4d0ba1682ad4cc2b0168c4c47b2e294e73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0190962204036709$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16627451$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15761427$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yang, Marjorie U.</creatorcontrib><creatorcontrib>Yaroslavsky, Anna N.</creatorcontrib><creatorcontrib>Farinelli, William A.</creatorcontrib><creatorcontrib>Flotte, Thomas J.</creatorcontrib><creatorcontrib>Rius-Diaz, Francisca</creatorcontrib><creatorcontrib>Tsao, Sandy S.</creatorcontrib><creatorcontrib>Anderson, R. Rox</creatorcontrib><title>Long-pulsed neodymium:yttrium-aluminum-garnet laser treatment for port-wine stains</title><title>Journal of the American Academy of Dermatology</title><addtitle>J Am Acad Dermatol</addtitle><description>Laser treatment of port-wine stain (PWS) might be improved using a deeply penetrating wavelength.
PWSs in 17 patients were treated 3 times with a 595-nm pulsed dye laser (PDL) and a 1064-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser. Fluences of 1.0, 0.8, and 0.6 times the minimum purpura dose (MPD) were used for Nd:YAG laser. Posttreatment biopsy specimens were taken. Blind assessment and quantitative analysis of PWS clearing were performed from digital photographs.
MPD for Nd:YAG laser varied widely, from 40 to 250 J/cm
2. Purpura lasted longer after PDL. Treatment achieved similar 50% to 75% clearing with both PDL and Nd:YAG laser at 1 MPD. Nd:YAG caused greater perivascular and epidermal injury. Scarring occurred in the only patient treated with a Nd:YAG fluence greater than 1 MPD. Patients preferred Nd:YAG laser because of their faster recovery.
Nd:YAG laser used at MPD is as effective as PDL for treating PWS. Nd:YAG laser fluences higher than MPD may cause scarring.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Hereditary diseases of the skin. Congenital diseases of the skin. Haemangioma of the skin, of mucosae and of soft tissue</subject><subject>Humans</subject><subject>Laser Therapy</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pilot Projects</subject><subject>Port-Wine Stain - pathology</subject><subject>Port-Wine Stain - radiotherapy</subject><issn>0190-9622</issn><issn>1097-6787</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFq3DAQhkVpabZpX6CH4ktz83Yky5IdegkhaQsLgdCexViaDVpseSPJLfv20bILufU0w_DNz8zH2GcOaw5cfdutd4huLQBkGaw7rd6wFYde10p3-i1bAe-h7pUQF-xDSjsA6GWj37ML3mrFpdAr9riZw1O9X8ZErgo0u8Pkl-n6kHMstcZxmXwozRPGQLkaMVGsciTME4VcbedY7eeY638-UJUy-pA-sndbLHmfzvWS_bm_-337s948_Ph1e7OpbdPJXNuhgRbajninWmwAW9LE7QACXIMkHQzIVSfQSWvFUB7urLRSD4JEL0k3l-zqlLuP8_NCKZvJJ0vjiOWPJRmlW1BNrwooTqCNc0qRtmYf_YTxYDiYo0mzM0eT5mjyOCsmy9KXc_oyTOReV87qCvD1DGCyOG4jBuvTK6eU0LLlhft-4qi4-OspmmQ9BUvOR7LZuNn_744XR_iSzw</recordid><startdate>20050301</startdate><enddate>20050301</enddate><creator>Yang, Marjorie U.</creator><creator>Yaroslavsky, Anna N.</creator><creator>Farinelli, William A.</creator><creator>Flotte, Thomas J.</creator><creator>Rius-Diaz, Francisca</creator><creator>Tsao, Sandy S.</creator><creator>Anderson, R. Rox</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050301</creationdate><title>Long-pulsed neodymium:yttrium-aluminum-garnet laser treatment for port-wine stains</title><author>Yang, Marjorie U. ; Yaroslavsky, Anna N. ; Farinelli, William A. ; Flotte, Thomas J. ; Rius-Diaz, Francisca ; Tsao, Sandy S. ; Anderson, R. Rox</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c384t-cb305058e1865a30a5e7e1cb020d3ae4d0ba1682ad4cc2b0168c4c47b2e294e73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Dermatology</topic><topic>Hereditary diseases of the skin. Congenital diseases of the skin. Haemangioma of the skin, of mucosae and of soft tissue</topic><topic>Humans</topic><topic>Laser Therapy</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pilot Projects</topic><topic>Port-Wine Stain - pathology</topic><topic>Port-Wine Stain - radiotherapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yang, Marjorie U.</creatorcontrib><creatorcontrib>Yaroslavsky, Anna N.</creatorcontrib><creatorcontrib>Farinelli, William A.</creatorcontrib><creatorcontrib>Flotte, Thomas J.</creatorcontrib><creatorcontrib>Rius-Diaz, Francisca</creatorcontrib><creatorcontrib>Tsao, Sandy S.</creatorcontrib><creatorcontrib>Anderson, R. Rox</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Academy of Dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yang, Marjorie U.</au><au>Yaroslavsky, Anna N.</au><au>Farinelli, William A.</au><au>Flotte, Thomas J.</au><au>Rius-Diaz, Francisca</au><au>Tsao, Sandy S.</au><au>Anderson, R. Rox</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-pulsed neodymium:yttrium-aluminum-garnet laser treatment for port-wine stains</atitle><jtitle>Journal of the American Academy of Dermatology</jtitle><addtitle>J Am Acad Dermatol</addtitle><date>2005-03-01</date><risdate>2005</risdate><volume>52</volume><issue>3</issue><spage>480</spage><epage>490</epage><pages>480-490</pages><issn>0190-9622</issn><eissn>1097-6787</eissn><coden>JAADDB</coden><abstract>Laser treatment of port-wine stain (PWS) might be improved using a deeply penetrating wavelength.
PWSs in 17 patients were treated 3 times with a 595-nm pulsed dye laser (PDL) and a 1064-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser. Fluences of 1.0, 0.8, and 0.6 times the minimum purpura dose (MPD) were used for Nd:YAG laser. Posttreatment biopsy specimens were taken. Blind assessment and quantitative analysis of PWS clearing were performed from digital photographs.
MPD for Nd:YAG laser varied widely, from 40 to 250 J/cm
2. Purpura lasted longer after PDL. Treatment achieved similar 50% to 75% clearing with both PDL and Nd:YAG laser at 1 MPD. Nd:YAG caused greater perivascular and epidermal injury. Scarring occurred in the only patient treated with a Nd:YAG fluence greater than 1 MPD. Patients preferred Nd:YAG laser because of their faster recovery.
Nd:YAG laser used at MPD is as effective as PDL for treating PWS. Nd:YAG laser fluences higher than MPD may cause scarring.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>15761427</pmid><doi>10.1016/j.jaad.2004.10.876</doi><tpages>11</tpages></addata></record> |
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| subjects | Adolescent Adult Biological and medical sciences Dermatology Hereditary diseases of the skin. Congenital diseases of the skin. Haemangioma of the skin, of mucosae and of soft tissue Humans Laser Therapy Medical sciences Middle Aged Pilot Projects Port-Wine Stain - pathology Port-Wine Stain - radiotherapy |
| title | Long-pulsed neodymium:yttrium-aluminum-garnet laser treatment for port-wine stains |
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