HCO3- secretion in the esophageal submucosal glands

The mammalian esophagus has the capacity to secrete a HCO(3)(-) and mucin-rich fluid in the esophageal lumen. These secretions originate from the submucosal glands (SMG) and can contribute to esophageal protection against refluxed gastric acid. The cellular mechanisms by which glandular cells achiev...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2005-04, Vol.288 (4), p.G736-G744
Hauptverfasser:	Abdulnour-Nakhoul, Solange, Nakhoul, Nazih L, Wheeler, Scott A, Wang, Paul, Swenson, Eric R, Orlando, Roy C
Format:	Artikel
Sprache:	eng
Schlagworte:	4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid - pharmacology Animals Anion Transport Proteins - antagonists & inhibitors Anion Transport Proteins - metabolism Bicarbonates - metabolism Biological Transport Carbonic Anhydrases - metabolism Chlorides - metabolism Cholinergic Agonists - pharmacology Esophagus - drug effects Esophagus - metabolism In Vitro Techniques Mucous Membrane Receptor, Muscarinic M1 - metabolism Serous Membrane - metabolism Swine
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