Bone marrow mesenchymal stem cells undergo nemosis and induce keratinocyte wound healing utilizing the HGF/c-Met/PI3K pathway

ABSTRACT We previously showed cell–cell contacts of human dermal fibroblasts to induce expression of the hepatocyte growth factor/scatter factor (HGF) in a process designated as nemosis. Now we report on nemosis initiation in bone marrow mesenchymal stem cells (BMSCs). Because BMSCs are being used i...

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Veröffentlicht in:	Wound repair and regeneration 2009-07, Vol.17 (4), p.569-577
Hauptverfasser:	Peura, Matti, Bizik, Jozef, Salmenperä, Pertteli, Noro, Ariel, Korhonen, Matti, Pätilä, Tommi, Vento, Antti, Vaheri, Antti, Alitalo, Riitta, Vuola, Jyrki, Harjula, Ari, Kankuri, Esko
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Communication - physiology Cell Line Cell Physiological Phenomena - physiology Cyclooxygenase 2 - metabolism Hepatocyte Growth Factor - metabolism Humans Keratinocytes - physiology Mesenchymal Stromal Cells - physiology Phosphatidylinositol 3-Kinases - physiology Proto-Oncogene Proteins c-met - physiology Signal Transduction Wound Healing - physiology
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