Video imaging system for automated shaping and analysis of complex locomotory behavior

Although many observational technologies have been developed for the study of behavior, most of these technologies have suffered from the inability to engender highly reproducible behaviors that can be observed and modified. We have developed ACROBAT (Automated Control in Real-Time of Operant Behavi...

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Veröffentlicht in:Journal of neuroscience methods 2009-08, Vol.182 (1), p.34-42
Hauptverfasser: Publicover, Nelson G., Hayes, Linda J., Fernando Guerrero, L., Hunter, Kenneth W.
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container_end_page 42
container_issue 1
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container_title Journal of neuroscience methods
container_volume 182
creator Publicover, Nelson G.
Hayes, Linda J.
Fernando Guerrero, L.
Hunter, Kenneth W.
description Although many observational technologies have been developed for the study of behavior, most of these technologies have suffered from the inability to engender highly reproducible behaviors that can be observed and modified. We have developed ACROBAT (Automated Control in Real-Time of Operant Behavior and Training), a video imaging system and associated computer algorithms that allow the fully automated shaping and analysis of complex locomotory behaviors. While this operant conditioning system is particularly useful for measuring the acquisition and maintenance of complex topographies, it also provides a more general and user friendly platform on which to develop novel paradigms for the study of learning and memory in animals. In this paper we describe the instrumentation and software developed, demonstrate the use of ACROBAT to shape a specific topography, and show how the system can be used to facilitate the study of arthritic pain in mice.
doi_str_mv 10.1016/j.jneumeth.2009.05.016
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Animals
Arthritis
Arthritis - diagnosis
Arthritis - physiopathology
Behavior
Female
Gait
Image Interpretation, Computer-Assisted - methods
Locomotion
Locomotory
Mice
Mice, Inbred BALB C
Monitoring, Ambulatory - methods
Operant conditioning
Pattern Recognition, Automated - methods
Photography - methods
Shaping
Video imaging
Video Recording - methods
title Video imaging system for automated shaping and analysis of complex locomotory behavior
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