The US smallpox vaccination program: a review of a large modern era smallpox vaccination implementation program
We describe the US experience with a large-scale smallpox vaccination program in the modern era and quantify the anticipated and unanticipated local and systemic side-effects of smallpox vaccination. In addition, we review unexpected issues, such as the development of myopericarditis discovered duri...
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| Veröffentlicht in: | Vaccine 2005-03, Vol.23 (17), p.2078-2081 |
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| container_title | Vaccine |
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| creator | Poland, Gregory A. Grabenstein, John D. Neff, John M. |
| description | We describe the US experience with a large-scale smallpox vaccination program in the modern era and quantify the anticipated and unanticipated local and systemic side-effects of smallpox vaccination. In addition, we review unexpected issues, such as the development of myopericarditis discovered during the implementation of this program. These results constitute the largest dataset of a vaccinia vaccination program utilizing calf-lymph derived New York City Board of Health strain vaccine (Dryvax, Wyeth) since the 1970s. These results should inform current and future vaccinia vaccination programs and provide a historical rate of complications against which candidate vaccine side-effects can be compared in future clinical trials. |
| doi_str_mv | 10.1016/j.vaccine.2005.01.012 |
| format | Article |
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These results should inform current and future vaccinia vaccination programs and provide a historical rate of complications against which candidate vaccine side-effects can be compared in future clinical trials.</description><subject>Animals</subject><subject>Bush, George W</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Cattle</subject><subject>Fatalities</subject><subject>Female</subject><subject>Health Personnel</subject><subject>Humans</subject><subject>Immunization</subject><subject>Male</subject><subject>Mass Vaccination - adverse effects</subject><subject>Mass Vaccination - methods</subject><subject>Military Personnel</subject><subject>Myocarditis - etiology</subject><subject>National Health Programs</subject><subject>Pericarditis - etiology</subject><subject>Pregnancy</subject><subject>Safety</subject><subject>Side effects</subject><subject>Smallpox</subject><subject>Smallpox vaccine</subject><subject>Smallpox Vaccine - adverse effects</subject><subject>Smallpox Vaccine - 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In addition, we review unexpected issues, such as the development of myopericarditis discovered during the implementation of this program. These results constitute the largest dataset of a vaccinia vaccination program utilizing calf-lymph derived New York City Board of Health strain vaccine (Dryvax, Wyeth) since the 1970s. These results should inform current and future vaccinia vaccination programs and provide a historical rate of complications against which candidate vaccine side-effects can be compared in future clinical trials.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>15755574</pmid><doi>10.1016/j.vaccine.2005.01.012</doi><tpages>4</tpages></addata></record> |
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| ispartof | Vaccine, 2005-03, Vol.23 (17), p.2078-2081 |
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| subjects | Animals Bush, George W Cardiovascular Diseases - etiology Cattle Fatalities Female Health Personnel Humans Immunization Male Mass Vaccination - adverse effects Mass Vaccination - methods Military Personnel Myocarditis - etiology National Health Programs Pericarditis - etiology Pregnancy Safety Side effects Smallpox Smallpox vaccine Smallpox Vaccine - adverse effects Smallpox Vaccine - isolation & purification Smallpox vaccine side effects United States Vaccines |
| title | The US smallpox vaccination program: a review of a large modern era smallpox vaccination implementation program |
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