Association of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma2 with decreased basic metabolic rate in women with polycystic ovary syndrome

The peroxisome proliferator-activated receptor (PPAR)gamma is a transcription factor involved in glucose homeostasis and energy metabolism. A missense mutation at codon 12 in the PPARgamma2 has been associated with increased body mass index (BMI) and attenuated insulin resistance (IR) in polycystic...

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Veröffentlicht in:	European journal of endocrinology 2009-08, Vol.161 (2), p.317-322
Hauptverfasser:	Koika, Vasiliki, Marioli, Dimitra J, Saltamavros, Alexandros D, Vervita, Vasiliki, Koufogiannis, Kleanthis D, Adonakis, George, Decavalas, George, Georgopoulos, Neoklis A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Basal Metabolism - genetics Blood Glucose - metabolism Calorimetry, Indirect Case-Control Studies DNA - chemistry DNA - genetics Female Genetic Variation Genotype Humans Insulin - blood Insulin Resistance - physiology Mutation, Missense Polycystic Ovary Syndrome - blood Polycystic Ovary Syndrome - genetics Polycystic Ovary Syndrome - metabolism Polymerase Chain Reaction Polymorphism, Restriction Fragment Length Polymorphism, Single Nucleotide PPAR gamma - genetics Statistics, Nonparametric Testosterone - blood Young Adult
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