Inherent specificities in natural antibodies: a key to immune defense against pathogen invasion

Natural antibodies are produced at tightly regulated levels in the complete absence of external antigenic stimulation. They provide immediate, early and broad protection against pathogens, making them a crucial non-redundant component of the humoral immune system. These antibodies are produced mainl...

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Veröffentlicht in:	Seminars in immunopathology 2005-03, Vol.26 (4), p.347-362
Hauptverfasser:	BAUMGARTH, Nicole, TUNG, James W, HERZENBERG, Leonore A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral - biosynthesis Antibody Specificity Autoantibodies - biosynthesis Autoantigens Autoimmunity B-Lymphocyte Subsets - immunology Biological and medical sciences Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunity, Innate Immunopathology Infection - immunology Influenza, Human - immunology Medical sciences Mice
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