Omental adipose tissue overexpression of fatty acid transporter CD36 and decreased expression of hormone-sensitive lipase in insulin-resistant women with polycystic ovary syndrome

BACKGROUND Elevated free fatty acids (FFAs) are involved in insulin resistance in polycystic ovary syndrome (PCOS). We investigated the role of fatty acid transporter CD36, hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL) in regulation of lipolysis in insulin-resistant women wit...

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Veröffentlicht in:	Human reproduction (Oxford) 2009-08, Vol.24 (8), p.1982-1988
Hauptverfasser:	Seow, Kok-Min, Tsai, Yieh-Loong, Hwang, Jiann-Loung, Hsu, Wei-Yen, Ho, Low-Tone, Juan, Chi-Chang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - metabolism Adult Biological and medical sciences Body fat CD36 CD36 Antigens - metabolism Fatty Acids, Nonesterified - metabolism Female free fatty acids Gynecology. Andrology. Obstetrics hormone-sensitive lipase Humans Insulin Resistance - physiology Lipase - metabolism Medical sciences Omentum - metabolism polycystic ovary syndrome Polycystic Ovary Syndrome - metabolism Sterol Esterase - metabolism
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