BK-{beta}1 subunit: immunolocalization in the mammalian connecting tubule and its role in the kaliuretic response to volume expansion

Large, Ca(2+)-activated K(+) channels (BK), comprised of alpha- and beta-subunits, mediate K(+) secretion during high flow rates in distal nephron segments. Because the BK-beta1 subunit enhances Ca(2+) sensitivity of BK in a variety of cells, we determined its role in flow-induced K(+) secretion and...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	American journal of physiology. Renal physiology 2005-04, Vol.288 (4), p.F846-F854
Hauptverfasser:	Pluznick, Jennifer L, Wei, Peilin, Grimm, P Richard, Sansom, Steven C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Female Immunohistochemistry Kidney Tubules, Collecting - physiology Large-Conductance Calcium-Activated Potassium Channels Male Mice Mice, Inbred C57BL Mice, Knockout Nephrons - physiology Potassium - urine Potassium Channels, Calcium-Activated - genetics Potassium Channels, Calcium-Activated - metabolism Rabbits
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!