Trophoblasts Isolated from the Maternal Circulation: In Vitro Expansion and Potential Application in Non-invasive Prenatal Diagnosis

Prenatal diagnosis based on rare fetal cells in maternal blood is currently not a feasible option. An effort was made to improve cell yields by targeting trophoblast cells. After sorting, the HLA-G-positive cell fraction was analyzed directly or after culture. In situ hybridization technology was ap...

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Veröffentlicht in:	The journal of histochemistry and cytochemistry 2005-03, Vol.53 (3), p.337-339
Hauptverfasser:	Guetta, Esther, Gutstein-Abo, Liat, Barkai, Gad
Format:	Artikel
Sprache:	eng
Schlagworte:	Centrifugation, Density Gradient Female Histocompatibility Antigens Class I - metabolism HLA Antigens - metabolism HLA-G Antigens Humans Immunomagnetic Separation In Situ Hybridization, Fluorescence Male Pregnancy Prenatal Diagnosis - methods Sex Determination Analysis - methods Trophoblasts - cytology Trophoblasts - metabolism
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