Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development

Establishment of the left-right axis is a fundamental process of vertebrate embryogenesis. Failure to develop left-right asymmetry leads to incorrect positioning and morphogenesis of numerous internal organs, and is proposed to underlie the etiology of several common cardiac malformations. The trans...

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Veröffentlicht in:	Development (Cambridge) 2005-03, Vol.132 (6), p.1337-1348
Hauptverfasser:	Weninger, Wolfgang J, Lopes Floro, Kylie, Bennett, Michael B, Withington, Sarah L, Preis, Jost I, Barbera, Juan Pedro Martinez, Mohun, Timothy J, Dunwoodie, Sally L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Patterning - physiology DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Genes, Reporter Heart - embryology Heart Defects, Congenital - genetics Humans Mice Mice, Transgenic Repressor Proteins - genetics Repressor Proteins - metabolism Trans-Activators - genetics Trans-Activators - metabolism
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